Immersive Virtual Reality Use in Medical Intensive Care: Mixed Methods Feasibility Study.
Brian W Locke, Te-Yi Tsai, C Mahony Reategui-Rivera...
https://pubmed.ncbi.nlm.nih.gov/39046869/Actively Recruiting
Led by Milton S. Hershey Medical Center · Updated on 2026-06-22
30
Participants Needed
1
Research Sites
N/A
Total Duration
This research investigates the use of immersive virtual reality VR therapy for adult patients in a surgical intensive care unit SICU. The study focuses on whether brief, calming VR sessions using a standalone head-mounted display can be safely and effectively integrated into routine SICU care. It explores potential effects of VR on anxiety, agitation, delirium, pain, and sedative medication needs, though it does not assess the safety or effectiveness of the VR equipment or software itself. Participants will experience non-interactive VR sessions showing soothing nature scenes such as beaches, forests, and mountains delivered through a commercially available VR headset and application. The intervention is behavioral and consists of short VR exposures during the ICU stay, applied within the usual clinical workflow. This pilot feasibility study aims to evaluate the practicality of delivering VR in this setting over an intervention period lasting up to 3 days. During the study, participants will be monitored for feasibility, acceptability, and appropriateness of the VR intervention using specific measures from enrollment until the end of the intervention at 3 days. Researchers will observe patient responses related to anxiety, delirium, agitation, and pain, alongside medication use. The total participation duration aligns with the ICU stay and the intervention timeframe, with continuous assessment to ensure patient comfort and safety throughout the VR sessions.
CONDITIONS
Virtual Reality to Reduce Anxiety, Agitation and Delirium in Critically Ill Patients
P
Pauline H Go, MD
A
Aleksandr Davtyan
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Milton S. Hershey Medical Center
Lead Sponsor
This table compares participation in this trial with other options available for this condition. The information is drawn from published research and the trial’s study details and is provided for educational purposes only.
| Factors | Virtual reality therapy sessions (Trial group) | Standard supportive care (Context) |
|---|---|---|
| What is it? | A behavioral intervention using immersive virtual reality (VR) headsets to deliver calming, non-interactive nature scenes (e.g., oceans, forests, mountains) during ICU stay. | Typical supportive care for ICU agitation, anxiety, and delirium prevention, which may include environmental controls, sleep promotion strategies, orientation, early mobilization, and pharmacologic or non-pharmacologic approaches as per current practice standards. |
| Role in the study or current care | Primary investigational intervention for all enrolled participants; study is designed to assess feasibility and acceptability of adding immersive VR therapy to ICU supportive care. | Forms the foundation of routine management in the SICU; does not include immersive VR therapy in usual clinical practice. |
| Primary use or purpose | To evaluate whether immersive VR therapy can feasibly and acceptably reduce anxiety, agitation, and delirium in critically ill adults during their ICU stay. | To prevent or manage anxiety, agitation, and delirium with established non-pharmacologic and pharmacologic strategies per clinical guidelines. |
| How is it given or performed? | Delivered using a commercially available VR headset with immersive nature-based audio-visual content. Sessions require patients to be alert enough to wear the headset, open their eyes, follow simple commands, and communicate discomfort. | Involves regular assessment by ICU staff, environmental optimization, orientation, family involvement, sleep hygiene, activity as tolerated, and medications when needed. No VR device is used in typical care. |
| Evidence maturity or status | Feasibility and acceptability of immersive VR therapy in the ICU are being investigated. Limited published pilot data exist for VR use to reduce anxiety/agitation, but broad clinical evidence or guidelines for routine use in this setting are not established. | Routine supportive care is established through published studies and guidelines as the standard approach for agitation, anxiety, and delirium prevention in critically ill ICU patients. |
| Important limitations | VR therapy cannot be used for ICU patients who are unable to follow commands, indicate discomfort, or who have severe sensory impairments, psychosis, severe dementia, vertigo, or acute hyperactive delirium. Effectiveness and safety for anxiety/agitation prevention remain under study; data are limited to small feasibility studies. | Standard supportive measures may not be fully effective for all patients, and pharmacologic interventions can have side effects or limited benefit in some cases. Non-pharmacologic measures require coordination and may be inconsistently applied. |
Disclaimer: This comparison is created with the help of artificial intelligence(AI) and may contain errors or missing information. It is not medical advice and does not mean one option is better or safer than another. Clinical trials are still being studied, and joining a trial is your choice. Please consult your healthcare professional before making any decisions.
You may qualify if you...
You will not qualify if you...
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Up to 3 days
Participants receive brief, calming virtual reality sessions using a commercial VR headset while admitted to the Surgical Intensive Care Unit.
Sessions delivered within routine ICU care
Duration - From enrollment to end of intervention at 3 days
Researchers assess feasibility, acceptability, and appropriateness of the VR intervention and explore patient symptoms and medication use during the intervention period.
Regular monitoring during ICU stay
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
PREVENTION
Number of Arms
1
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Lead Sponsor