Actively Recruiting

Age: 25Years - 35Years
FEMALE
Healthy Volunteers
NCT06910293

Whole-Brain Dynamics in the Natural Menstrual Cycle vs. an Ovarian Stimulated Cycle: Impact of Hormonal Fluctuations on Healthy Women Undergoing Ovarian Stimulation

Led by ART Fertility Clinics LLC · Updated on 2025-06-10

15

Participants Needed

2

Research Sites

86 weeks

Total Duration

On this page

Sponsors

A

ART Fertility Clinics LLC

Lead Sponsor

K

Khalifa University for Science and Technology

Collaborating Sponsor

AI-Summary

What this Trial Is About

The investigators aim is to investigate the brain's dynamic complexity across three phases of an ovarian stimulation cycle (basal, pre-OPU, mid-luteal), to observe the impact of externally administered hormones, and compare it with the corresponding phases of a natural menstrual cycle (early follicular, pre-ovulatory, mid-luteal) in the same woman. Brain activity patterns will be examined using resting-state fMRI in a sample of young, healthy, naturally cycling women.

CONDITIONS

Official Title

Whole-Brain Dynamics in the Natural Menstrual Cycle vs. an Ovarian Stimulated Cycle: Impact of Hormonal Fluctuations on Healthy Women Undergoing Ovarian Stimulation

Who Can Participate

Age: 25Years - 35Years
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age group: 25 - 35 years old
  • Body Mass Index (BMI) between 20 and 30
  • Anti-Mullerian Hormone (AMH) level between 1.3 and 5.9 ng/ml
  • Regular menstrual cycle lasting 26 to 35 days
  • At least 3 months wash-out period after any previous use of hormonal contraception
  • Meet safety and eligibility standards for MRI scanning, including no metallic implants or claustrophobia
Not Eligible

You will not qualify if you...

  • History of ovarian surgery
  • Any ovarian pathology
  • Mental health disorders
  • Use of medications that affect brain function
  • Current use of hormonal contraception including pills, patches, or Mirena IUD

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

ART Fertility Clinics LLC

Abu Dhabi, Abu Dhabi Emirate, United Arab Emirates, 00000

Actively Recruiting

2

ART Fertility Clinics LLC

Abu Dhabi, Abu Dhabi Emirate, United Arab Emirates, 60202

Actively Recruiting

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Research Team

R

Raquel Del Gallego, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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