Study of Brain Function and Psychological Effects in Adults With Autoimmune Hemolytic Anemia Receiving Cell Therapy

What this Trial Is About

Researchers are evaluating the effects of cell therapy on brain function and psychological well-being in patients with autoimmune hemolytic anemia AIHA. This observational study aims to detect any cognitive or behavioral changes that may occur due to cell therapy, such as CAR T-cell therapy, to help develop safer and more effective treatment methods and improve patients quality of life. Participants will undergo brain function and psychological assessments before receiving cell therapy and then again on Days 1, 4, 7, 10, 14, 21, and 28 after treatment. These assessments will monitor changes in oxygenated and de-oxygenated hemoglobin levels, psychological status, anxiety, depression symptoms, sleep quality, and physical fatigue throughout the study period. During the study, patients will regularly complete evaluations measuring brain oxygen levels and various psychological and physical symptoms at multiple time points. This close monitoring helps detect any changes early, allowing timely interventions. The study is conducted by the Institute of Hematology & Blood Diseases Hospital, and participation lasts for at least 28 days following cell therapy.

Brain Function and Psychological Changes Related to Cell Therapy for Autoimmune Hemolytic Anemia