Actively Recruiting

Age: 18Years +
All Genders
Healthy Volunteers
ID06449443

Zero Echo Time MR for the Assessment of Maxillary Sinus, Bone and Soft Tissues in the Maxillary Premolar and Molar Areas

Led by Hacettepe University · Updated on 2024-10-01

20

Participants Needed

2

Research Sites

26 weeks

Total Duration

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AI-Summary

What this Trial Is About

Researchers are evaluating zero echo time magnetic resonance imaging (ZTE MRI) as a diagnostic tool to assess both hard and soft tissues and the maxillary sinus region before dental implants in the posterior maxillary area. This study aims to provide an ionizing radiation-free alternative to cone beam computed tomography (CBCT), which is commonly used but exposes patients to radiation and does not adequately evaluate soft tissues. The research focuses on patients with missing teeth in specific upper jaw regions to improve treatment planning for dental implants. Participants will undergo both CBCT and ZTE MRI scans, and measurements will be taken digitally with an intraoral scanner and directly during surgery. The study will compare bone and soft tissue measurements from these methods to evaluate ZTE MRI's effectiveness. The evaluation period spans from the start to 18 months, covering assessments of the maxillary sinus area, alveolar bone dimensions, and gingival tissue dimensions relevant to implant planning. During the study, participants will have imaging procedures and direct surgical measurements to collect data on bone and soft tissue conditions. Researchers will analyze these results to determine the accuracy of ZTE MRI compared to CBCT and direct measurements. The study includes patients aged 18 and older with missing teeth in the maxillary premolar and molar areas, and it involves monitoring over an 18-month period to assess the diagnostic method's usefulness.

CONDITIONS

Brief Title

Zero Echo Time MR for the Assessment of Maxillary Sinus and Dental Regions

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Missing teeth in the maxillary premolar and molar regions
  • Available cone-beam computed tomography images of the tooth-deficient area
  • No systemic diseases affecting periodontal tissues such as diabetes or rheumatoid arthritis
  • Age 18 years or older
  • Provided informed consent to participate
Not Eligible

You will not qualify if you...

  • All maxillary teeth missing
  • Active periodontitis (gum inflammation)
  • Under 18 years of age
  • Did not provide informed consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Diagnostic Evaluation

Duration - Baseline to 18 months

Participants undergo imaging assessments including zero echo time magnetic resonance imaging (ZTE MRI) and cone beam computed tomography (CBCT) to evaluate bone and soft tissues in the maxillary premolar and molar areas before dental implant treatment.

Trial Site Locations

Total: 2 locations

1

Department of Periodontology, Faculty of Dentistry, Hacettepe University,

Ankara, Turkey (Türkiye), 06100

Actively Recruiting

2

Hacettepe University Faculty of Medicine

Ankara, Turkey (Türkiye), 06230

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Research Team

G

Guliz Nigar Guncu, DDS PhD

U

Ustun Aydingoz, MD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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