Actively Recruiting
7.0T Magnetic Resonance Imaging Study of Parkinson's Disease
Led by Chinese PLA General Hospital · Updated on 2024-11-08
200
Participants Needed
1
Research Sites
156 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are investigating the imaging characteristics of Parkinson's Disease (PD) using 7-Tesla (7T) magnetic resonance imaging (MRI). The study aims to detect subtle changes in patients with a short history of PD compared to healthy individuals, explore imaging differences among PD subtypes, and identify neuroimaging biomarkers that can distinguish these subtypes. This observational study also includes a long-term follow-up to assess the relationship between imaging changes and clinical symptom progression. Participants will undergo 7T-MRI scanning to capture detailed brain images. The study focuses on comparing imaging data from different PD subtypes and healthy subjects to understand functional and structural brain connectivity alterations. Follow-up imaging and clinical assessments will be conducted over several years to monitor changes and their correlation with motor symptoms. During the study, participants will have regular MRI scans and clinical evaluations to track motor symptoms and brain connectivity features. Researchers will measure changes in motor function five years after enrollment, alongside clinical and imaging variables. The study includes healthy volunteers and patients with PD, with ongoing observation to link imaging findings to disease progression and motor symptom changes.
CONDITIONS
Brief Title
7.0T Magnetic Resonance Imaging Study of Parkinson's Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients diagnosed with Parkinson's Disease by an experienced neurologist specializing in movement disorders
You will not qualify if you...
- Patients with brain disorders such as cerebrovascular disease, brain tumors, epilepsy, or other neurodegenerative diseases
- Patients with psychiatric disorders affecting cognitive function
- Patients with contraindications to MRI
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Short term
Participants undergo 7T-MRI scanning to detect imaging characteristics related to Parkinson's Disease.
1 visit (in-person)
Duration - Up to 5 years
Participants are followed over time to evaluate changes in imaging results and clinical motor symptoms.
Follow-up visits over 5 years
Trial Site Locations
Total: 1 location
1
Chinese PLA General Hospital
Beijing, Beijing, China, China, 100853
Actively Recruiting
Research Team
H
Haoxaun Lu
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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