Status:
COMPLETED
Women's Angiographic Vitamin and Estrogen Trial (WAVE)
Lead Sponsor:
National Heart, Lung, and Blood Institute (NHLBI)
Conditions:
Cardiovascular Diseases
Coronary Arteriosclerosis
Eligibility:
FEMALE
38-86 years
Phase:
PHASE3
Brief Summary
To assess whether hormonal replacement therapy and/or antioxidant treatment would stabilize or inhibit progression, and induce regression of coronary plaques. The mechanisms by which these treatments ...
Detailed Description
BACKGROUND: Coronary artery disease is the leading cause of death in the United States, accounting for over 500,000 deaths each year. Although the onset of coronary artery disease is delayed in women...
Eligibility Criteria
Postmenopausal women, up to age 86, with angiographically documented coronary artery disease of at least 15 percent, but no more than 75 percent occlusion.
Key Trial Info
Start Date :
August 1 1996
Trial Type :
INTERVENTIONAL
End Date :
May 1 2003
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00000555
Start Date
August 1 1996
End Date
May 1 2003
Last Update
July 12 2016
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