Quantification of three-dimensional left ventricular segmental wall motion and volumes from gated tomographic radionuclide ventriculograms.
T L Faber, E M Stokely, G H Templeton...
https://pubmed.ncbi.nlm.nih.gov/2785584Completed
All Genders
Healthy Volunteers
ID00001459
Tomographic Myocardial Wall Motion Analysis in Patients With Myocardial Ischemia and in Normal Subjects
Led by National Heart, Lung, and Blood Institute (NHLBI) · Updated on 2008-03-04
150
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Myocardial ischemia is a heart condition in which not enough blood supply and oxygen reaches the heart muscle. Damage to the major blood vessels of the heart (coronary artery disease), minor blood vessels of the heart (microvascular heart disease), or damage to the heart muscle (hypertrophic cardiomyopathy) can cause myocardial ischemia. Any of theses three conditions can cause patients to experience chest pain and other symptoms as well as cause the heart to function improperly. In order to detect myocardial ischemia researchers can use tests to measure the movement of the walls of the heart. Walls receiving inadequate supplies of blood often move less and occasionally move in the opposite direction. Some of the tests may require patients to receive injections of radioactive tracers. The radioactive material acts to enhance 3 dimensional pictures of the heart and helps to identify areas of ischemia. The purpose of this study is to determine whether 3-dimensional imaging (tomography) with radioactive tracers can provide more important information about heart wall function than routine diagnostic tests.
CONDITIONS
Official Title
Analysis of Heart Muscle Function in Patients With Heart Disease and Normal Volunteers
Who Can Participate
All Genders
Healthy Volunteers
Eligibility Criteria
You may qualify if you...
Patients with known coronary artery disease (obstruction of greater than or equal to 50% in at least one major coronary artery).
Patients with hypertrophic cardiomyopathy.
Patients with microvascular angina.
No unstable angina.
No hepatic or renal failure.
Infective endocarditis
No primary valvular disease.
No congenital heart disease.
No pregnant or breast feeding women.
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
Trial Site Locations
Total: 1 location
1
National Heart, Lung and Blood Institute (NHLBI)
Bethesda, Maryland, United States, 20892
Status Unknown
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How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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Published Research Related To This Trial
Tomographic gated blood pool radionuclide ventriculography: analysis of wall motion and left ventricular volumes in patients with coronary artery disease.
J R Corbett, D E Jansen, S E Lewis...
https://pubmed.ncbi.nlm.nih.gov/2991357Sensitivity, specificity and predictive accuracy of radionuclide cineangiography during exercise in patients with coronary artery disease. Comparison with exercise electrocardiography.
J S Borer, K M Kent, S L Bacharach...
https://pubmed.ncbi.nlm.nih.gov/455620