Completed

Phase Not Applicable
Age: 50Years - 85Years
All Genders
Healthy Volunteers
ID00175084

Effect of Dietary Amino Acid Profile on Lipoprotein Metabolism, Vascular Reactivity and Inflammatory Markers

Led by Tufts University · Updated on 2014-05-23

30

Participants Needed

1

Research Sites

287 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The aim of this study is to explore the significance of the Lys:Arg ratio on responses of lipids and lipoprotein concentrations to dietary proteins and to evaluate the effects of dietary Lys:Arg on cardiovascular disease risk factors and endothelial function.

CONDITIONS

Official Title

Effect of Dietary Amino Acid Profile on Lipoprotein Metabolism, Vascular Reactivity and Inflammatory Markers

Who Can Participate

Age: 50Years - 85Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age: 50-85 years
  • LDL-C concentrations >120 mg/dL
Not Eligible

You will not qualify if you...

  • Use of medications known to affect lipid metabolism
  • Established cardiovascular disease
  • Renal disease
  • Liver disease
  • Thyroid disease unless controlled with medication for at least 6 months
  • Type I and II diabetes
  • Irritable bowel syndrome
  • Chronic use of prescription anti-inflammatory medications
  • Smoking
  • Alcohol intake >7 alcoholic drinks per week
  • Unwillingness to maintain body weight during participation in the study
  • triglyceride (TG) > 400 mg/dL
  • Unwillingness to adhere to diet and study protocol
  • Weight gain or loss of more than 15 lb within 6 months prior to enrollment

Trial Site Locations

Total: 1 location

1

Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University

Boston, Massachusetts, United States, 02111

Status Unknown

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

PREVENTION

Number of Arms

0

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