Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
ID07315672

Acupressure for Cough in Lung Cancer Survivors: A Randomized Controlled Trial

Led by The University of Hong Kong · Updated on 2026-05-22

80

Participants Needed

2

Research Sites

8 weeks

Total Duration

On this page

Sponsors

T

The University of Hong Kong

Lead Sponsor

T

The University of Hong Kong-Shenzhen Hospital

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are evaluating the effects of acupressure on cough and related symptoms such as shortness of breath and fatigue in lung cancer survivors. This randomized controlled trial aims to see if acupressure can reduce these symptoms, improve symptom burden, and enhance health-related quality of life and functional ability in patients with lung cancer. The study addresses the significant impact that cough and its related symptoms have on lung cancer survivors' quality of life and overall survival. Participants are randomly assigned to one of two groups: one group receives an 8-week acupressure intervention, while the other receives an educational booklet about lung cancer, cough causes, and management. The acupressure group attends two hospital training sessions in the first week to learn the technique, then performs acupressure daily on 15 specific points twice a day and during coughing episodes as needed. The education group receives the booklet after baseline assessment and will be offered acupressure later after the study ends. Participants keep diaries of their acupressure practice and symptoms and are assessed four times: before starting (baseline), after one week, after eight weeks, and eight weeks after the intervention ends. Researchers measure cough, quality of life related to cough, symptom clusters, fatigue, shortness of breath, symptom burden, functional capacity, and overall health-related quality of life. Follow-up continues for 16 weeks to monitor lasting effects and safety throughout the study period.

CONDITIONS

Brief Title

Acupressure for Cough in Lung Cancer Survivors

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Be at least 18 years old
  • Have a diagnosis of lung cancer at any stage and any pathological type
  • Have a cough symptom rating of 3 or higher on a 0 to 10 scale within 7 days before enrollment
  • Be able to perform acupressure independently during daily activities
  • Be able to read Chinese and communicate in Cantonese or Mandarin
  • Be able to provide informed consent
Not Eligible

You will not qualify if you...

  • Have unstable chronic diseases other than lung cancer
  • Have received acupressure or acupuncture in the 3 months before enrollment
  • Have serious illnesses or conditions preventing following intervention protocols
  • Have a life expectancy of less than 3 months
  • Currently participating in other research that may affect study outcomes

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Outpatient Treatment

Duration - 8 weeks

Participants in the acupressure group will attend two hospital training sessions in the first week to learn correct acupressure techniques. They will then perform acupressure daily for 8 weeks, pressing specific acupoints twice a day and as needed during cough episodes. Trainers will follow up twice weekly by phone or face-to-face to support and assess their practice. Participants in the education group will receive an educational booklet and complete evaluations alongside the acupressure group.

2 training sessions and twice-weekly follow-up contacts during 8 weeks

Follow-up

Duration - 8 weeks

After completing the 8-week intervention, participants are followed for an additional 8 weeks to assess the lasting effects of the intervention on cough and related symptoms.

Visits at 16 weeks after baseline

Trial Site Locations

Total: 2 locations

1

University of Hong Kong-Shenzhen Hospital

Shenzhen, Guangdong, China, 0755

Actively Recruiting

2

Queen Mary Hospital

Hong Kong, Hong Kong, 0000

Not Yet Recruiting

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Research Team

M

Mengyao Cao

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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Frequently Asked Questions

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The value of a symptom cluster of fatigue, dyspnea, and cough in predicting clinical outcomes in lung cancer survivors.

Andrea L Cheville, Paul J Novotny, Jeffrey A Sloan...

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