Actively Recruiting
Adaptive Decision-making And Personalized Treatment for PTSD (ADAPT-PTSD)
Led by The University of Texas Health Science Center at San Antonio · Updated on 2025-12-19
302
Participants Needed
4
Research Sites
139 weeks
Total Duration
On this page
Sponsors
T
The University of Texas Health Science Center at San Antonio
Lead Sponsor
U
United States Department of Defense
Collaborating Sponsor
AI-Summary
What this Trial Is About
By doing this research project, the investigators hope to learn which strategies work best to help veterans who are not benefiting from their first PTSD treatment or not completing between-session homework assignments regularly that might improve treatment response. The investigators also want to learn how best to match the right type and amount of treatment to each individual veteran. By conducting this research project, they hope to: * See if trying a different treatment strategy for veterans not responding to their first PTSD treatment would be more helpful * See if sending text message prompts between sessions encourages more completion of between-session homework
CONDITIONS
Official Title
Adaptive Decision-making And Personalized Treatment for PTSD (ADAPT-PTSD)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Veterans eligible for Prolonged Exposure (PE) and Cognitive Processing Therapy (CPT) at the participating PTSD treatment clinic
- At least 18 years old
- Score 31 or higher on the PCL-5 due to a Criterion A traumatic event
- Own a mobile device compatible with therapy companion apps (PE Coach or CPT Coach)
You will not qualify if you...
- Acute suicide risk requiring clinical intervention
- Need for detoxification
- Unmanaged psychosis or bipolar disorder
- Severe cognitive impairment affecting ability to follow study procedures
- Current or past 12-month participation in Prolonged Exposure (PE) or Cognitive Processing Therapy (CPT)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 4 locations
1
Augusta VA
Augusta, Georgia, United States, 30904
Actively Recruiting
2
Ann Arbor VA
Ann Arbor, Michigan, United States, 48105
Actively Recruiting
3
Battle Creek VA
Battle Creek, Michigan, United States, 49037
Not Yet Recruiting
4
Salt Lake City VA
Salt Lake City, Utah, United States, 84148
Actively Recruiting
Research Team
S
Stefanie LoSavio, PhD
CONTACT
R
Rebecca Sripada, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
SEQUENTIAL
Primary Purpose
TREATMENT
Number of Arms
8
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