Actively Recruiting

Age: 18Years +
All Genders
NCT06459115

Adherence to Medication in Patients With Acute Decompensated Heart Failure

Led by Universität des Saarlandes · Updated on 2024-06-20

100

Participants Needed

1

Research Sites

99 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Every day, patients present to emergency department due to acute heart failure. There are many causes for decompensation. One possible cause is a lack of adherence to heart failure medication (prognosis-improving medications and diuretics). The aim of this study is to directly measure adherence in patients with acute heart failure (gold standard of adherence measurement using liquid chromatography coupled to high-resolution mass spectrometry= LC-HRMS/MS) at the emergency department. Questionnaires are used to investigate possible factors influencing adherence.

CONDITIONS

Official Title

Adherence to Medication in Patients With Acute Decompensated Heart Failure

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • 18 years of age or older
  • Known chronic heart failure regardless of ejection fraction
  • Requirement of intravenous diuretics (outpatient or inpatient)
  • Stable heart failure medication for more than 2 weeks
  • At least one sign of volume overload (peripheral edema, jugular venous distension, pulmonary rales, ascites, or pulmonary venous congestion shown on chest X-ray)
  • Elevated natriuretic peptides (N-terminal pro brain natriuretic peptide \u2265125 pg/ml)
Not Eligible

You will not qualify if you...

  • Unable to provide written informed consent

AI-Screening

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Trial Site Locations

Total: 1 location

1

Department of Internal Medicine III, Cardiology, Angiology and Intensive Care Medicine, University Hospital Saarland, Saarland University

Homburg, Germany, 66421

Actively Recruiting

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Research Team

F

Felix Mahfoud, Professor

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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