Actively Recruiting

Age: 18Years +
All Genders
Healthy Volunteers
ID07580612

Artificial Intelligence-Driven Freezing Of Gait Detection in the Home: Investigating How Free-living Activities Affect the Algorithm

Led by KU Leuven · Updated on 2026-05-12

126

Participants Needed

3

Research Sites

N/A

Total Duration

On this page

Sponsors

K

KU Leuven

Lead Sponsor

M

Michael J. Fox Foundation for Parkinson's Research

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are evaluating an artificial intelligence (AI) algorithm designed to detect freezing of gait (FOG) episodes in people with Parkinson's disease, a symptom that increases the risk of falling. The study aims to test this AI algorithm in a home environment, which is less controlled than laboratory settings, to see if it can accurately identify FOG episodes. The collected data will also be used to improve the AI's ability to detect FOG automatically and explore real-time detection capabilities. Participants include people with Parkinson's disease who experience daily FOG, those who do not experience FOG, and healthy older adults as controls. The study involves free-living gait assessments over two days, each lasting 5 hours, followed by a standardized gait assessment lasting 4 hours on the third day. The AI algorithm's performance will be compared to expert video analysis, considered the gold standard, across these different walking tests. During the study, participants will wear inertial measurement unit (IMU) sensors to collect movement data while walking in their home environment and during standardized tests. Researchers will measure the percentage of time spent freezing, the number of FOG episodes, and the algorithm's ability to distinguish different types of FOG and medication states. The study also evaluates the consistency of detection between assessments and the occurrence of false detections. Participation includes multiple days of monitoring, and safety and adherence will be closely tracked throughout the study period.

CONDITIONS

Brief Title

AID-FOG: Artificial Intelligence-Driven Freezing of Gait Detection in the Home

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Voluntary written informed consent obtained before any study procedures
  • At least 18 years old at the time of consent
  • Cognitively able to understand instructions and provide consent
  • Able to walk about 10 meters independently, with or without a walking aid
  • Does not live in a temporary or permanent care facility
  • Clinical diagnosis of Parkinson's disease by a neurologist (for Parkinson's participants)
  • Self-reports daily freezing of gait (for participants recruited as freezers)
  • Willing to temporarily delay morning anti-Parkinsonian medication during assessment visit
Not Eligible

You will not qualify if you...

  • Experienced myocardial infarction, unstable angina, stroke, coronary artery bypass graft, percutaneous coronary intervention, or cardiac resynchronization therapy device implantation within 3 months prior to consent
  • Under active treatment for cancer or other malignant disease
  • Has uncontrolled congestive heart disease (NYHA class >3)
  • Has acute psychosis, major psychiatric disorders, or ongoing substance abuse
  • Has other neurological or orthopedic conditions significantly affecting gait
  • Self-reports daily falls
  • Participating in another interventional study involving investigational drugs or devices

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Diagnostic Evaluation

Duration - 3 days

Participants undergo assessments to evaluate freezing of gait using free-living and standardized gait tests.

3 visits over 3 days (in-person assessments of gait)

Long-term Monitoring

Duration - 1 week

Participants wear sensors for one week to monitor free-living mobility and freezing of gait episodes.

Continuous monitoring with wearable sensors at home

Trial Site Locations

Total: 3 locations

1

Department of Rehabilitation Sciences

Leuven, Belgium, 3001

Actively Recruiting

2

Sports Science and Neurorehabilitation

Hamburg, Germany, 20457

Not Yet Recruiting

3

Center for the study of movement, cognition and mobility

Tel Aviv, Israel, 64

Not Yet Recruiting

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How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

3

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Published Research Related To This Trial

Freezing of gait assessment with inertial measurement units and deep learning: effect of tasks, medication states, and stops.

Po-Kai Yang, Benjamin Filtjens, Pieter Ginis...

https://pubmed.ncbi.nlm.nih.gov/38350964