Actively Recruiting
Analysis of the Prevalence of Sensitization to Plants Containing Gibberellins Using Realistic Skin Prick Tests in Patients at Montpellier University Hospital
Led by University Hospital, Montpellier · Updated on 2025-10-03
2000
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are investigating the prevalence of sensitization to gibberellin-related proteins (GRPs), which are found in both pollens and certain foods like peaches, apples, sesame, carrots, lemons, and oranges. These proteins are linked to an increased risk of severe food allergy reactions, especially in regions with high exposure to specific pollens such as those from the Cupressaceae family. The study aims to better understand sensitization profiles to these allergens to improve allergy management, focusing on patients attending the Allergy Unit at the University Hospital of Montpellier. The study involves performing specific skin prick tests using raw forms of six foods containing GRPs: peach, apple, sesame, carrot, lemon, and orange. Participants will undergo testing during their allergy evaluation visit. This observational assessment will help identify who is sensitized to these proteins and explore potential cross-sensitization between the different plants and foods. Participants aged 5 years and older consulting for any allergy evaluation will be involved in the study. Researchers will assess sensitization through skin prick tests and measure the prevalence of sensitization to these six foods and cypress pollen. They will also examine IgE antibody positivity to the peach allergen Pru p 7 in sensitized patients and correlate sensitization with reported symptoms. The study's primary outcome is measured in one day during the allergy consultation.
CONDITIONS
Brief Title
Analysis of the Prevalence of Sensitization to Plants Containing Gibberellins Using Realistic Skin Prick Tests
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients aged at least 5 years
- Patients consulting at the Allergy Unit of the University Hospital of Montpellier for any allergy evaluation
- Oral consent from the patient and legal representatives if the patient is a minor
You will not qualify if you...
- Treatment with antihistamines or psychotropic drugs with antihistaminic action within 7 days before inclusion
- Pathologies preventing prick tests (e.g., severe peripheral neuropathy, cutaneous anergy)
- Presence of dermographism
- Participation in another study that may affect prick test results
- Being in an exclusion period from a previous study
- Pregnant, parturient, or breastfeeding women
- Under court protection, guardianship, or trusteeship
- Not covered by a health insurance scheme
- Inability to read and understand French fluently
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - 1 day
Participants undergo specific skin prick tests for six raw foods: peach, apple, sesame, carrot, lemon, and orange to assess sensitization.
1 visit (in-person)
Trial Site Locations
Total: 1 location
1
University Hospital of Montpellier
Montpellier, France, 34295
Actively Recruiting
Research Team
D
Davide CAIMMI, MD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
OTHER
Number of Arms
1
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