Actively Recruiting
Anesthesia Induction with the Target-controlled Infusion of Propofol in High-risk Patients
Led by Acibadem University · Updated on 2025-02-03
200
Participants Needed
1
Research Sites
43 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to compare the risk of hypotension following induction of anesthesia in high-risk patients (American Society of Anesthesiologists risk scores III and IV) using target-controlled infusion (TCI) of propofol versus standard manual induction of anesthesia. Our previously published study compared TCI and manual induction of anesthesia in a general patient population and found that hypotension developed less with TCI induction. This study is a continuation of the other study and will be conducted in high-risk patients.
CONDITIONS
Official Title
Anesthesia Induction with the Target-controlled Infusion of Propofol in High-risk Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with the American Society of Anesthesiology physical status 3-4
- Underwent major elective surgery
- Required intra-arterial blood pressure monitoring before induction.
You will not qualify if you...
- Under 18 years of age
- Patients with the American Society of Anesthesiology physical status 1-2
- Arrhythmia (atrial fibrillation, frequent premature beat)
- Severe valvular heart disease
- Morbid obesity
- Intubation difficulty
- Drug addiction
- Treatment with opiates
- Pregnancy
- Emergency surgery
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Acibadem Altunizade Hospital
Istanbul, Turkey (Türkiye)
Actively Recruiting
Research Team
S
Serap A Aktas Yildirim, MD
CONTACT
Z
Zeynep Tugce Sarikaya, M.D.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SCREENING
Number of Arms
2
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