Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT04833335

ASL in Brain Metastasis MRI Following Gamma Knife Treatment

Led by Assistance Publique - Hôpitaux de Paris · Updated on 2025-08-08

60

Participants Needed

1

Research Sites

295 weeks

Total Duration

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AI-Summary

What this Trial Is About

Arterial spin labeling (ASL) is a non-invasive MRI technique that could help the radiologists to distinguish brain metastasis progression versus radionecrosis following gamma-knife treatment. The primary target of the study is to establish the diagnostic performances (specificity, sensitivity) of quantitative measures of ASL in brain metastases suspected of progression/radionecrosis after GK treatment

CONDITIONS

Official Title

ASL in Brain Metastasis MRI Following Gamma Knife Treatment

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Brain metastasis from histologically proven tumor
  • GK treatment within 4 month prior to the inclusion
  • Lesions suspected of progression or radionecrosis with at least 25% size progression
  • Lesion size with gadolinium enhanced part of the tumor of 1 cm or larger
Not Eligible

You will not qualify if you...

  • Pregnancy
  • Medical history of primitive brain tumor
  • MRI incompatibility or history of contrast agent allergy
  • Claustrophobia
  • Patient unable to consent
  • Epilepsy or recent stroke
  • Participation in other studies
  • No health care insurance

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Service de neuroradiologie, hôpital Pitié Salpêtrière

Paris, France, 75013

Actively Recruiting

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Research Team

N

Natalia SHOR, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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