Actively Recruiting
Long-Term Clinical Evaluation of Aspiration Thrombectomy Using the Symphony or Prodigy Thrombectomy System - CLEAR-IT
Led by Imperative Care, Inc. · Updated on 2026-05-18
750
Participants Needed
2
Research Sites
26 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to evaluate how well the Symphony and Prodigy thrombectomy systems work and how safe they are when used in procedures to remove blood clots from different parts of the body, including the peripheral arteries, peripheral veins, and pulmonary (lung) blood vessels. The study focuses on both short-term and long-term results to better understand these devices' clinical performance across these vascular areas. Participants will undergo aspiration thrombectomy procedures using either the Symphony or Prodigy thrombectomy systems to remove clots from the peripheral arterial vasculature, peripheral venous vasculature, or pulmonary vasculature. The study includes separate groups for each vascular area. Each group receives treatment with the appropriate system designed for their clot location. During the study, participants will be followed for various time points including up to 180 days to assess outcomes such as procedural success and safety. Researchers will collect data at multiple intervals including during the procedure, shortly after, at hospital discharge, and at 30, 90, and 180 days. The study involves ongoing follow-up to monitor clinical results and device performance over time, helping to provide a comprehensive understanding of the treatments.
CONDITIONS
Brief Title
Aspiration Thrombectomy Using the Symphony or Prodigy System
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Subject is 18 years of age or older
- Willing and able to follow the study's follow-up schedule
- Willing and able to provide written informed consent before any study data collection
- Has a planned procedure using Imperative Care vascular devices within their intended use
You will not qualify if you...
- Has any contraindications according to the device Instructions for Use
- Life expectancy less than 1 year
- Considered not suitable for intervention with Imperative Care devices by the investigator
- Unable to complete study follow-up
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Procedure day
Participants undergo aspiration thrombectomy using the Symphony or Prodigy Thrombectomy System to remove thrombus from the peripheral arterial, peripheral venous, or pulmonary vasculature.
1 procedure visit
Duration - Up to 180 days
Participants are monitored for up to 180 days after the thrombectomy procedure to assess clinical outcomes and device performance.
Multiple follow-up visits up to 180 days
Trial Site Locations
Total: 2 locations
1
Huntsville Hospital
Huntsville, Alabama, United States, 35801
Actively Recruiting
2
Profound Research
Munster, Illinois, United States, 46321
Actively Recruiting
Research Team
S
Sylvie Akiel-Fu, MPH
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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