Actively Recruiting
Assessment of Thyroid Dysfunction in Patients Undergoing Haemodialysis at Sohag University Hospital
Led by Sohag University · Updated on 2025-06-15
1
Participants Needed
1
Research Sites
28 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Thyroid dysfunction is a prevalent endocrine disorder that significantly impacts the health of patients with chronic kidney disease (CKD), particularly those undergoing dialysis. The prevalence of thyroid dysfunction in dialysis patients has been reported to range from 20% to 60%, highlighting the need for routine screening and management in this vulnerable group (Kuo et al., 2024). Thyroid hormones play a crucial role in regulating various physiological processes, and their dysregulation can lead to complications such as cardiovascular disease, anemia, and impaired quality of life, which are particularly concerning in the dialysis population (Smith et al., 2024). The relationship between CKD and thyroid dysfunction is complex and multifactorial. Uremic toxins can interfere with the hypothalamic-pituitary-thyroid axis, leading to alterations in thyroid hormone production and metabolism. Recent studies have shown that inflammation and oxidative stress associated with CKD can further exacerbate thyroid dysfunction (Johnson et al., 2024). Understanding these mechanisms is essential for developing effective management strategies for thyroid health in dialysis patients.
CONDITIONS
Official Title
Assessment of Thyroid Dysfunction in Patients Undergoing Haemodialysis at Sohag University Hospital
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18 years and older
- Diagnosed with end-stage renal disease (ESRD) and receiving regular hemodialysis for at least 3 months
You will not qualify if you...
- History of thyroid disease before starting dialysis
- Received thyroid dysfunction treatment within the last 6 months
- Acute kidney injury or not on regular dialysis
- Pregnant or breastfeeding women
- Using medications or having illnesses that affect thyroid function tests, such as corticosteroids or lithium
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Hospital
Sohag, Egypt
Actively Recruiting
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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