Critical care and the global burden of critical illness in adults.
Neill K J Adhikari, Robert A Fowler, Satish Bhagwanjee...
https://pubmed.ncbi.nlm.nih.gov/20934212Actively Recruiting
Led by Ankara University · Updated on 2024-07-31
100
Participants Needed
1
Research Sites
4 weeks
Total Duration
A
Ankara University
Lead Sponsor
G
Gazi University
Collaborating Sponsor
Researchers are studying how different ventilation parameters like mechanical power, driving pressure, and elastic power can help predict how long critically ill patients on invasive mechanical ventilation will need support. This observational study includes patients recently intubated for acute respiratory failure and aims to improve decisions about when to safely remove breathing tubes or prepare for alternatives like tracheostomy. The study monitors these ventilation values at the start of mechanical ventilation, and again at 24 and 48 hours, to see how well they predict extubation within the first week. By including all patients on invasive ventilation, the research looks beyond specific conditions like ARDS to better understand risks across a broad ICU population. Participants will be observed during their ICU stay with regular assessments of their ventilator settings and clinical condition. Researchers will track outcomes such as the timing of extubation within seven days, mortality at 28 days, development of acute kidney failure within a month, and length of ICU or hospital stay over three months. This approach aims to guide early treatment planning and improve patient management in critical care.
CONDITIONS
Assessment of Ventilation Parameters for Extubation Prediction in ICU
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Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - First 7 days after intubation
Participants who are under invasive mechanical ventilation have their ventilation parameters measured and monitored at specific timepoints to predict extubation within the first week.
Visits at 0, 24, and 48 hours after intubation
Duration - Up to 3 months
Participants are observed for clinical outcomes including mortality, acute renal failure, and length of ICU/hospital stay.
Follow-up visits up to 3 months after intubation
Total: 1 location
1
Ankara University Faculty of Medicine
Altindağ, Ankara, Turkey (Türkiye), 06230
Actively Recruiting
N
nuri işler, res.doctor
N
Nazlıhan B DÜNDAR, Ass.Prof.
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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