Actively Recruiting

Phase Not Applicable
Age: 18Years - 35Years
All Genders
Healthy Volunteers
NCT04041154

Behavioral and Neural Representations of Subjective Effort Cost

Led by Hugo W. Moser Research Institute at Kennedy Krieger, Inc. · Updated on 2026-01-26

185

Participants Needed

1

Research Sites

595 weeks

Total Duration

On this page

Sponsors

H

Hugo W. Moser Research Institute at Kennedy Krieger, Inc.

Lead Sponsor

N

National Institute of Mental Health (NIMH)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this proposal is to understand the common and distinct behavioral and neural representations of subjective effort valuation, and how these representations are influenced by fatigue and changes in motivation. It is hypothesized that the brain will use overlapping and distinct neural circuits to represent cognitive and physical effort value, and that fatigue and enhanced motivation will influence the subjective value of effort.

CONDITIONS

Official Title

Behavioral and Neural Representations of Subjective Effort Cost

Who Can Participate

Age: 18Years - 35Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Right-handed
  • Age between 18 and 35 years old
  • Male or female
  • Any ethnicity
Not Eligible

You will not qualify if you...

  • History of neurological problems such as stroke, head injury, epilepsy, seizures, brain tumors, brain surgery, Parkinson's Disease
  • Diagnosed history of severe psychiatric disease such as depression or schizophrenia
  • Presence of metal in the head or eyes
  • Pregnancy or suspected pregnancy
  • Discomfort from MRI scans such as severe claustrophobia or excessive heating of tattoos

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Kennedy Krieger Institute

Baltimore, Maryland, United States, 21209

Actively Recruiting

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Research Team

A

Anthony Gonzalez

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

BASIC_SCIENCE

Number of Arms

3

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