Study on Vaginal and Sexual Health in Women After Radiotherapy for Anal Cancer Observing Effects and Support 6 to 36 Months Post-Treatment

What this Trial Is About

This research aims to understand how radiotherapy for anal cancer affects vaginal and sexual health in women after treatment. It focuses on how often moderate to severe vaginal narrowing occurs, whether radiation dose to the vagina is linked to vaginal problems, and how these changes impact sexual health and daily life. The study also evaluates the care and support women receive after treatment and their satisfaction with it. Participants are women aged 18 years or older who received chemotherapy and radiotherapy aimed at curing anal cancer and are between 6 and 36 months post-treatment. Researchers will review radiotherapy scans to measure vaginal radiation exposure. Some participants will join a telephone interview to share their experiences with post-treatment guidance and support. During the study visit, participants will have a gynecological exam to check for vaginal changes like narrowing, stiffness, bleeding, or scarring. They will complete online questionnaires about sexual health and quality of life and answer questions about vaginal dilator use, hormone treatment, and sexual counseling. The main outcome measured is the prevalence of moderate to severe vaginal narrowing after treatment. The study plans to include about 80 women across several hospitals, with around 20 participating in interviews to better understand patient support needs.

Beyond Survival: Addressing Gynecological and Sexual Health in Women After Radiotherapy for Anal Cancer