Actively Recruiting
Ultrasound-Guided Bilateral Erector Spinae Plane Block Versus Bilateral Oblique Subcostal Transversus Abdominis Plane Block for Postoperative Analgesia in Colorectal Surgery: A Prospective Randomized Study
Led by Cairo University · Updated on 2026-05-22
50
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are comparing two types of pain relief techniques, the ultrasound-guided bilateral erector spinae plane block (ESPB) and the oblique subcostal transverse abdominal plane block (OSTAPB), for managing pain after colorectal surgery. Colorectal surgery treats various digestive system conditions, including cancers and inflammatory diseases. ESPB is a newer method targeting specific spinal nerves, while OSTAPB involves injecting anesthetics between abdominal muscle layers. Participants will receive either the ESPB or OSTAPB using ultrasound guidance before their colorectal surgery under general anesthesia. The study randomly assigns patients to one of these two groups to evaluate which method provides better pain control after surgery. Both treatments involve local anesthetic injections to block nerve signals responsible for pain. During the study, participants will be monitored for pain levels 24 hours after surgery, time until first need for additional pain medication, and overall opioid use. Heart rate, blood pressure, patient satisfaction, recovery quality, and any adverse events will also be tracked during and after surgery. The total participation period includes intraoperative monitoring and 24 hours postoperatively.
CONDITIONS
Brief Title
Bilateral Erector Spinae Plane Block Versus Bilateral Oblique Subcostal Transversus Abdominis Plane Block for Postoperative Analgesia in Colorectal Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 to 75 years old
- Both sexes
- American Society of Anesthesiologists (ASA) physical status II-III
- Scheduled for open colorectal surgery under general anesthesia
You will not qualify if you...
- History of opioid abuse
- Chronic opioid consumption
- Body mass index (BMI) 35 kg/m2 or higher
- Severe cardiac insufficiency classified as New York Heart Association (NYHA) class III or IV heart failure
- Renal failure with estimated glomerular filtration rate (eGFR) less than 30 mL/min/1.73 m2
- Hepatic encephalopathy
- Skin infection at or near the puncture site
- Coagulopathy defined as platelet count less than 100,000/mm3, INR greater than 1.5, or use of anticoagulant therapy that cannot be stopped
- Allergy to drugs used in the study
- History of previous or recurrent laparoscopic cholecystectomy procedures
AI-Screening
AI-Powered Screening
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Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 2 hours (duration of surgery)
Participants receive either ultrasound-guided erector spinae plane block or oblique subcostal transversus abdominis plane block during colorectal surgery under general anesthesia.
1 visit (in-person, surgery day)
Duration - 24 hours postoperatively
Participants are monitored for pain degree, analgesia use, vital signs, patient satisfaction, recovery quality, and adverse events for 24 hours after surgery.
1 follow-up visit within 24 hours after surgery
Trial Site Locations
Total: 1 location
1
Cairo University
Cairo, Egypt, 12613
Actively Recruiting
Research Team
M
Mohammed M Alarousy, MSc
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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