Evaluating Heart Function in Children Ages 2 to 14 With Steroid Dependent or Steroid Resistant Nephrotic Syndrome Using Tissue Doppler Imaging and Echocardiography

What this Trial Is About

Nephrotic syndrome is a common kidney disease in children, and patients with primary nephrotic syndrome have a higher risk of developing heart disease compared to the general population. This research evaluates cardiac function in children with two types of nephrotic syndrome steroid dependent and steroid resistant. The study aims to better understand how heart performance differs between these groups using advanced imaging techniques. The study uses Tissue Doppler imaging alongside Conventional Echocardiography, both non-invasive methods that measure the motion velocity of specific heart structures like the mitral annulus, tricuspid annulus, and interventricular septum. Participants are randomly assigned to one of two groups based on their nephrotic syndrome type steroid dependent or steroid resistant. These imaging assessments help compare cardiac performance between these groups. Children aged 2 to 14 years with primary nephrotic syndrome will participate, undergoing heart imaging and monitoring over 12 months. Researchers will evaluate cardiac function changes using the specified imaging techniques. Throughout the study, participants heart health will be closely observed to gather detailed information on cardiac performance related to their nephrotic syndrome type.

Cardiac Performance Evaluation in Children With Steroid Dependent vs Steroid Resistant Nephrotic Syndrome