Actively Recruiting
Cardiovascular Responses in Burn Survivors During Exercise
Led by University of Texas Southwestern Medical Center · Updated on 2025-07-18
36
Participants Needed
1
Research Sites
103 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This project will identify the efficacy of cooling modalities aimed to attenuate excessive elevations in skin and internal body temperatures, and associated indices of cardiovascular stress, during physical activity in well-healed burn survivors. The investigators will conduct a randomized crossover design study. Non-burned control subjects and subjects who experienced burns covering 20% or more of their body surface area will be investigated. Subjects will exercise in heated environmental conditions while receiving no cooling (control) as well as skin wetting.
CONDITIONS
Official Title
Cardiovascular Responses in Burn Survivors During Exercise
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Healthy male and female subjects
- Aged 18 to 65 years
- Free of any underlying medical conditions
- For burn survivors: burn injury covering 20% or more of body surface area
- For burn survivors: at least 50% of burn injuries are full thickness requiring skin grafting
- For burn survivors: hospitalization due to burn injury for a minimum of 15 days
You will not qualify if you...
- Any burn-related injuries resulting in at least one night of hospitalization (for non-burned individuals)
- Heart disease or other chronic medical conditions requiring regular medical therapy including cancer, diabetes, and hypertension
- Abnormalities detected on routine screening
- Participation in structured aerobic exercise training programs at moderate to high intensities
- Current smokers or those who regularly smoked within the past 3 years
- Body mass index greater than 30 kg/m2
- Pregnant individuals
- Extensive unhealed injured skin (for burn survivors)
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Institute for Exercise and Environmental Medicine - Texas Health Presbyterian Hospital Dallas
Dallas, Texas, United States, 75231
Actively Recruiting
Research Team
E
Erin M Harper, B.S.
CONTACT
C
Craig G Crandall, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
CROSSOVER
Primary Purpose
OTHER
Number of Arms
2
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