Actively Recruiting

Age: 16Years +
All Genders
NCT06234410

Cardiovascular Risk Assessment For Kidney Transplantation - Utility of Computed Tomography Coronary Angiography in the Assessment of Patients Awaiting Kidney Transplantation

Led by University of Edinburgh · Updated on 2026-02-13

332

Participants Needed

2

Research Sites

414 weeks

Total Duration

On this page

Sponsors

U

University of Edinburgh

Lead Sponsor

C

Chief Scientist Office of the Scottish Government

Collaborating Sponsor

AI-Summary

What this Trial Is About

Cardiovascular disease (for example, heart attack, stroke, heart failure) is the commonest complication of kidney failure. Kidney transplantation reduces cardiovascular risk but cardiovascular disease remains the commonest cause of death in patients following transplantation. Current strategies to assess patient's cardiovascular risk prior to kidney transplantation do not identify those at highest risk and do not improve outcomes. This study will use a heart scan known as computed tomography coronary angiography (CTCA) to see whether this scan can identify patients at highest risk of future cardiovascular disease prior to transplantation. Studies have shown it is able to do this in patients with normal kidney function. The aim of this study is to develop CTCA as an effective tool to risk stratify patients prior to kidney transplantation.

CONDITIONS

Official Title

Cardiovascular Risk Assessment For Kidney Transplantation - Utility of Computed Tomography Coronary Angiography in the Assessment of Patients Awaiting Kidney Transplantation

Who Can Participate

Age: 16Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Has kidney failure and is on the waitlist for a kidney transplant
  • Age 16 years and over
  • Able to give informed consent
Not Eligible

You will not qualify if you...

  • Contraindication to CT scanning, including contrast allergy
  • Patients being considered for a simultaneous kidney-pancreas, kidney-liver and/or kidney-islet transplantation
  • Inability to give informed consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Royal Infirmary of Edinburgh

Edinburgh, Lothian, United Kingdom, EH16 4SA

Actively Recruiting

2

Queen Elizabeth Hospital

Glasgow, United Kingdom, G51 4TF

Not Yet Recruiting

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Research Team

G

Gavin B Chapman, MBChB

CONTACT

N

Neeraj Dhaun, MBChB

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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Cardiovascular Risk Assessment For Kidney Transplantation - Utility of Computed Tomography Coronary Angiography in the Assessment of Patients Awaiting Kidney Transplantation | DecenTrialz