Using Computed Tomography Coronary Angiography to Assess Heart Disease Risk in Adults Awaiting Kidney Transplant

What this Trial Is About

Cardiovascular disease, such as heart attack, stroke, and heart failure, is the most common complication in people with kidney failure. Even after kidney transplantation, cardiovascular disease remains the leading cause of death. Current methods to assess cardiovascular risk before kidney transplantation do not effectively identify those at highest risk or improve outcomes. This research aims to develop a heart scan called computed tomography coronary angiography CTCA as a tool to better assess cardiovascular risk in patients waiting for a kidney transplant. Participants in this study will undergo a single CTCA scan before their kidney transplantation. This scan uses radiation to create detailed images of the hearts arteries. The study focuses on patients who have been placed on the kidney transplant waiting list in Scotland. The goal is to see if CTCA can help predict which patients are at higher risk of cardiovascular problems after transplantation. During the study, researchers will follow participants for up to 60 months after the CTCA scan. They will track important outcomes like heart attacks, cardiovascular deaths, hospitalizations due to heart events, and overall survival. The study will also assess how well CTCA identifies patients at risk, helping improve risk management before and after kidney transplantation.

Cardiovascular Risk Assessment For Kidney Transplantation - Utility of Computed Tomography Coronary Angiography in the Assessment of Patients Awaiting Kidney Transplantation