Study of Gut Bacteria and Their Impact on Growth and Immune Health in Children Ages 1 to 3 Living at High and Low Altitudes

What this Trial Is About

This research aims to understand how microbes interact with the human body, focusing on childrens gut bacteria in different regions, altitudes, and diets. It studies the development and changes in gut bacteria of children living in high-altitude plateau areas and compares them with children living at low altitudes to explore links with immunity, metabolism, and growth. The goal is to provide scientific insights to improve childrens health in high-altitude regions. Participants include children aged 1 to 3 years living either in high-altitude areas above 3000 meters or low-altitude areas below 500 meters. The study is observational and involves collecting fecal samples for gut microbiome and metabolite analysis within 7 days after enrollment. Researchers also use questionnaires to gather information on lifestyle, diet, and physical activity. During the study, children provide samples and may answer questions about their lifestyles. Researchers analyze the gut bacteria composition and metabolites to understand how these relate to growth and immune function. The study also monitors differences between children from high- and low-altitude regions. Participation involves cooperation from the childs legal guardian throughout the study process.

Characteristics of Intestinal Bacteria and Their Effects on Growth and Immune Function in Children at High Altitude