Prognostic value of ambulatory blood-pressure recordings in patients with treated hypertension.
Denis L Clement, Marc L De Buyzere, Dirk A De Bacquer...
https://pubmed.ncbi.nlm.nih.gov/12802026Actively Recruiting
Age: 18Years - 75Years
All Genders
Healthy Volunteers
ID06663267
Acute Effects of Meteorological Factors and Air Pollution on Cardiovascular Health
Led by The Affiliated Hospital of Hangzhou Normal University · Updated on 2024-10-29
350000
Participants Needed
1
Research Sites
52 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating how meteorological factors and air pollution affect the cardiovascular system in an observational study. The study aims to understand both the individual and combined impacts of weather conditions and air pollution on heart and blood vessel health, analyzing data from people with various exposures. It focuses on acute effects and includes adults aged 18 to 75 years. Participants are grouped based on their exposure to different temperature and pollution levels, including those experiencing high summer temperatures, low winter temperatures, high pollution, and low pollution areas. The study uses existing health data from physical exams and diagnostic tests without introducing new treatments or interventions. During the study, researchers collect and analyze health information such as blood pressure, blood and urine tests, ultrasound results, electrocardiograms, and cardiac CT scans. They monitor several key health measures like troponin levels and blood pressure at baseline before exposure and follow up at one and two years after exposure. This approach helps assess changes in heart function and related health markers over time.
CONDITIONS
Brief Title
Acute Effects of Meteorological Factors and Air Pollution on Cardiovascular Health
Who Can Participate
Age: 18Years - 75Years
All Genders
Healthy Volunteers
Eligibility Criteria
You may qualify if you...
- Relevant physical examination records available at least 3 times
- Age 18 years or older
You will not qualify if you...
- Relevant physical examination records fewer than 3 times
- Serious heart and lung diseases
- Malignant tumors
- History of serious mental illness
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
1
2
3
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Diagnostic Evaluation
Duration - 3 months before exposure
Participants undergo baseline health assessments including physical exams, blood tests, electrocardiograms, and imaging to collect cardiovascular and biochemical data before exposure to meteorological factors and air pollution.
At least 3 physical examination visits
Long-term Monitoring
Duration - Up to 2 years after exposure
Participants are monitored for cardiovascular health outcomes over time following exposure to meteorological factors and air pollution.
Follow-up assessments at 1 year and 2 years after exposure
Trial Site Locations
Total: 1 location
1
MingWei Wang
Hanzhou, Zhejiang, China, 310000
Actively Recruiting
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Research Team
M
Mingwei W Wang, PhD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
4
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Published Research Related To This Trial
Blood pressure in young adulthood and mortality from cardiovascular disease.
P McCarron, G D Smith, M Okasha...
https://pubmed.ncbi.nlm.nih.gov/10791531Association of Ambient Air Pollution with Blood Pressure in Adolescence: A Systematic-review and Meta-analysis.
Saniya Tandon, Antonio Jose Grande, Alexis Karamanos...
https://pubmed.ncbi.nlm.nih.gov/36265590