Actively Recruiting
China Inherited Ventricular Arrhythmias Registry, a Multicenter, Observational and Prospective Study
Led by China National Center for Cardiovascular Diseases · Updated on 2019-03-26
500
Participants Needed
1
Research Sites
260 weeks
Total Duration
On this page
Sponsors
C
China National Center for Cardiovascular Diseases
Lead Sponsor
R
Renmin Hospital of Wuhan University
Collaborating Sponsor
AI-Summary
What this Trial Is About
This research aims to build a risk stratification system for malignant inherited ventricular arrhythmias, including Brugada syndrome, Long QT syndrome, Short QT syndrome, Early repolarization syndrome, and Catecholaminergic polymorphic ventricular tachycardia. It is a prospective, observational, multi-center registry involving 500 participants recruited from 10 centers across China. The study focuses on exploring the relationship between genetic factors and clinical features to improve diagnosis and risk assessment of these inherited heart rhythm conditions. Participants diagnosed with one of the specified inherited ventricular arrhythmias will be enrolled and followed every 6 months. Clinical data such as medical history, laboratory tests, imaging, medications, and procedures will be collected from medical records. Blood samples will also be taken to analyze genes and other biological markers that might help identify risk indicators for these conditions. Throughout the study, participants will be interviewed and assessed regularly to monitor their arrhythmia status, medication use, and any clinical events. The primary outcome measured is the occurrence of sustained tachycardia, ventricular fibrillation, or sudden cardiac death over five years. Secondary outcomes include episodes of arrhythmia and all-cause mortality. This long-term follow-up aims to gather comprehensive data to better understand and manage malignant inherited ventricular arrhythmias.
CONDITIONS
Brief Title
China Inherited Ventricular Arrhythmias Registry
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosed with Brugada syndrome, Long QT syndrome, Short QT syndrome, Early repolarization syndrome, or Catecholaminergic polymorphic ventricular tachycardia.
You will not qualify if you...
- Currently enrolled in other clinical trials.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - At study entry
Participants provide medical history, clinical data, and biological samples to explore genotype-phenotype correlations for inherited ventricular arrhythmias.
1 visit (in-person)
Duration - Up to 5 years
Participants are followed every 6 months to track arrhythmia condition, medication, and clinical events over time.
Follow-up visits every 6 months
Trial Site Locations
Total: 1 location
1
China National Center for Cardiovascular Diseases
Beijing, Beijing Municipality, China, 100037
Actively Recruiting
Research Team
Y
Yan YAO, MD,PhD
S
Shangyu LIU, MD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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