Actively Recruiting

Phase Not Applicable
Age: 18Years - 80Years
All Genders
NCT04797572

Clinical Evaluation of the Free Margin Cusp Sizer (CALIBRATE)

Led by Cliniques universitaires Saint-Luc- Université Catholique de Louvain · Updated on 2025-05-16

120

Participants Needed

1

Research Sites

353 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The objective of this study is to investigate safety and performance of the Free Margin Cusp sizer. The device will be used during aortic valve repair and sparing procedures as a caliper to measure the aortic valve free margin length at different stages of the procedure. The patient will be followed for one year clinically (at 1, 2, 6 and 12 months) and by echocardiography (at 6 and 12 months) to assess aortic valve function.

CONDITIONS

Official Title

Clinical Evaluation of the Free Margin Cusp Sizer (CALIBRATE)

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with Tricuspid Aortic Valve operated electively for aortic valve regurgitation and/or ascending aorta dilation
Not Eligible

You will not qualify if you...

  • Acute aortic dissection
  • Diffuse aortic valve calcification
  • Aortic valve endocarditis
  • Bicuspid, unicuspid, or quadricuspid aortic valves
  • Patients under 18 years of age
  • Patients over 80 years of age

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Cliniques Universitaires Saint-Luc

Brussels, Belgium, 1200

Actively Recruiting

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Research Team

L

Laurent de Kerchove, MD, PhD

CONTACT

C

Corinne Coulon

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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