Actively Recruiting
CMT Gait, Mobility, Balance - AOFAS Grant
Led by Bopha Chrea · Updated on 2025-09-23
66
Participants Needed
1
Research Sites
72 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The overall objective of the proposed research is to begin to better understand the potential benefits and limitations of ankle -foot orthosis (AFO) use in the context of mobility and balance during gait for individuals with Charcot-Marie-Tooth disease (CMT). These benefits will be studied in comparison to those offered by surgical correction. We will accomplish by having subjects undergo mobility and balance tests in our gait analysis lab.
CONDITIONS
Official Title
CMT Gait, Mobility, Balance - AOFAS Grant
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Clinical diagnosis and genetic confirmation of Charcot-Marie-Tooth disease (CMT)
- Age between 12 and 75 years
- Able to walk at a slow to moderate pace without using an ankle-foot orthosis (AFO)
- Able to read and write in English and provide written informed consent
- For NonOP group: prescribed an AFO for daily activities
- For OP group: have had surgical correction of CMT cavovarus foot deformity focusing on muscle balancing and hindfoot correction
You will not qualify if you...
- Other causes or risk factors for peripheral neuropathy such as diabetes or alcohol abuse
- Uncorrected visual impairment
- History of musculoskeletal injury requiring surgery
- Loss of plantar protective sensation
- Pain greater than 4 out of 10 while walking or an increase in pain greater than 2 out of 10 during testing
- Concern by the examiner that the individual will not complete the study
- For NonOP group: previous surgical correction of CMT cavovarus foot deformity focusing on muscle balancing and hindfoot correction
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Iowa Medical Campus - North Liberty (MCNL)
North Liberty, Iowa, United States, 52713
Actively Recruiting
Research Team
B
Bopha Chrea, MD
CONTACT
L
Lauren Crowe, BS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
CROSSOVER
Primary Purpose
OTHER
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here