Actively Recruiting

Age: 18Years +
All Genders
ID06899867

Is Cardiac Index, Assessed by Transpulmonary Thermodilution, Reliable During Liver Transplantation Compared to Transesophageal Echocardiography: a Monocentric Cohort

Led by Hospices Civils de Lyon · Updated on 2025-03-28

30

Participants Needed

1

Research Sites

69 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Liver transplantation involves complex changes in blood flow during different surgical stages, which can make monitoring heart function challenging. Researchers are comparing two common monitoring methods: transpulmonary thermodilution and transesophageal echocardiography, to see how they track changes in cardiac index during liver transplant surgery. This observational study evaluates these methods to understand their reliability throughout the procedure. Participants undergoing liver transplantation are monitored using both thermodilution and transesophageal echocardiography at four key surgery stages: after anesthesia begins, during the anhepatic phase, at reperfusion, and during the surgical anastomosis of the biliary ducts. Measurements include cardiac index values before and after an end-expiratory occlusion test, along with echocardiographic visualization of the surgical anastomosis to assess blood flow and vessel diameter. During the study, patients have their heart function and blood flow monitored closely at these specific time points. Researchers collect demographic, biological, and post-operation data to analyze alongside cardiac measurements. The main outcome is comparing cardiac index changes measured by the two methods at these surgical stages to assess their consistency and reliability in the liver transplant setting.

CONDITIONS

Brief Title

Comparing Montiroing Cardiac Index by Transpulmonary Thermodilution and Transesophageal Echocardiography During Liver Transplantation

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults
  • Undergoing liver transplantation
Not Eligible

You will not qualify if you...

  • Oesophageal varice ligation less than 14 days ago
  • History of mediastinal radiotherapy
  • Femoral bypass
  • Severe lower extremity artery disease

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Diagnostic Evaluation

Duration - Duration of the liver transplantation surgery

Participants undergo monitoring of cardiac index using transpulmonary thermodilution and transesophageal echocardiography during liver transplantation surgery.

Measurements taken at 4 times during surgery

Trial Site Locations

Total: 1 location

1

Croix Rousse Hsopital

France, Lyon, France, 69004

Actively Recruiting

Loading map...

Research Team

P

Pr Alice Blet

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

Similar Trials

A Home-based Exercise and Physical Activity Intervention Aft...

Liver Transplantation

Actively Recruiting

1 location

ADDICTOlogical Intervention in LIVEr Transplantation Recipie...

Alcohol Associated Liver Disease

Actively Recruiting

16 locations

Effect of Temporary Porto-caval Shunt During Liver Transplan...

Liver Transplantation

Actively Recruiting

6 locations

Frequently Asked Questions

Have more questions? Get in touch with our team for quick support

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here