Actively Recruiting
Is Cardiac Index, Assessed by Transpulmonary Thermodilution, Reliable During Liver Transplantation Compared to Transesophageal Echocardiography: a Monocentric Cohort
Led by Hospices Civils de Lyon · Updated on 2025-03-28
30
Participants Needed
1
Research Sites
69 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Liver transplantation involves complex changes in blood flow during different surgical stages, which can make monitoring heart function challenging. Researchers are comparing two common monitoring methods: transpulmonary thermodilution and transesophageal echocardiography, to see how they track changes in cardiac index during liver transplant surgery. This observational study evaluates these methods to understand their reliability throughout the procedure. Participants undergoing liver transplantation are monitored using both thermodilution and transesophageal echocardiography at four key surgery stages: after anesthesia begins, during the anhepatic phase, at reperfusion, and during the surgical anastomosis of the biliary ducts. Measurements include cardiac index values before and after an end-expiratory occlusion test, along with echocardiographic visualization of the surgical anastomosis to assess blood flow and vessel diameter. During the study, patients have their heart function and blood flow monitored closely at these specific time points. Researchers collect demographic, biological, and post-operation data to analyze alongside cardiac measurements. The main outcome is comparing cardiac index changes measured by the two methods at these surgical stages to assess their consistency and reliability in the liver transplant setting.
CONDITIONS
Brief Title
Comparing Montiroing Cardiac Index by Transpulmonary Thermodilution and Transesophageal Echocardiography During Liver Transplantation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults
- Undergoing liver transplantation
You will not qualify if you...
- Oesophageal varice ligation less than 14 days ago
- History of mediastinal radiotherapy
- Femoral bypass
- Severe lower extremity artery disease
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Duration of the liver transplantation surgery
Participants undergo monitoring of cardiac index using transpulmonary thermodilution and transesophageal echocardiography during liver transplantation surgery.
Measurements taken at 4 times during surgery
Trial Site Locations
Total: 1 location
1
Croix Rousse Hsopital
France, Lyon, France, 69004
Actively Recruiting
Research Team
P
Pr Alice Blet
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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