Actively Recruiting
Complex And Simple Appendicitis: REstrictive or Liberal Post-operative Antibiotic eXposure - UCSF
Led by University of California, San Francisco · Updated on 2025-05-08
145
Participants Needed
1
Research Sites
160 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to demonstrate the safety, efficacy, and feasibility of short-course post-operative antibiotic treatment for simple and complicated appendicitis
CONDITIONS
Official Title
Complex And Simple Appendicitis: REstrictive or Liberal Post-operative Antibiotic eXposure - UCSF
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Planned appendectomy surgery, either laparoscopic or open
- Have a working telephone number or reliable method to be contacted after hospital discharge
You will not qualify if you...
- Unable to give consent
- Pregnant women
- Prisoners
- Immunocompromised patients, including those on steroids, chemotherapy, immunosuppressing medications, with active blood cancers, leukopenia, or end-stage AIDS
- Heart failure
- Allergy to bupivacaine
- Unlikely to comply with treatment or follow-up
- Inpatient consultation for appendicitis
- Clinically suspected sepsis based on Sepsis-3 definition
- Current use of antibiotics for other reasons
- Type 1 diabetes or uncontrolled high blood sugar
- Surgeon preference
- Patient preference
- Research team unavailable
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Zuckerberg San Francisco General Hospital
San Francisco, California, United States, 94110
Actively Recruiting
Research Team
L
Lucy Kornblith, MD
CONTACT
B
Brenda Nunez-Garcia
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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