Actively Recruiting
Contribution of Transthoracic and Transcranial Ultrasonography to the Titration of PEEP in Patients With ARDS and ABI
Led by Theodoros Schizodimos · Updated on 2025-12-31
30
Participants Needed
1
Research Sites
82 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The present study will investigate whether the combined use of lung and brain ultrasonography is useful in selecting the optimal positive end-expiratory pressure in mechanically ventilated critically ill patients with acute respiratory distress syndrome and acute brain injury, aiming at an individualized, brain-protective ventilation strategy.
CONDITIONS
Official Title
Contribution of Transthoracic and Transcranial Ultrasonography to the Titration of PEEP in Patients With ARDS and ABI
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Severe acute brain injury such as traumatic brain injury, subarachnoid hemorrhage, intracerebral hemorrhage, or acute ischemic stroke
- Development of acute respiratory distress syndrome (ARDS) according to Berlin criteria within the first 10 days of ICU admission
You will not qualify if you...
- Severe chronic brain diseases
- Presence of brain tumor or central nervous system infection
- Severe chronic pulmonary or cardiovascular disease
- Severe coagulopathy
- Undergoing decompressive craniectomy
- Lack of invasive neuromonitoring
- Withdrawal of life-sustaining treatment
- Poor acoustic window for ultrasound
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
George Papanikolaou General Hospital
Thessaloniki, Greece, 54248
Actively Recruiting
Research Team
T
Theodoros Schizodimos, MD
CONTACT
G
Georgia Pitsiou, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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