Correlation Between Postoperative Pain and Apical Extrusion of Different Irrigation Activation Techniques Randomized Controlled Trial - an In Vitro Study

What this Trial Is About

Researchers are evaluating the effects of different irrigant activation techniques on postoperative pain in patients with vital teeth suffering from symptomatic irreversible pulpitis. This trial also assesses the amount of debris extrusion at the root tip, which may relate to pain levels after treatment. The study includes several methods for activating root canal irrigants to compare their impact on patient discomfort and debris removal. Participants will receive one of four treatments: laser activation using a diode laser, sonic activation with a polyamide EDDY tip, ultrasonic activation with an ED60 tip, or passive irrigation using a side-vented endodontic needle. Each technique involves specific timing and movement protocols for activating the irrigant within the root canal, followed by irrigation with a 17% EDTA solution. The trial combines a randomized controlled clinical study with an in vitro analysis of debris extrusion. During the study, participants will report their pain levels before and after treatment at multiple time points: 8, 24, and 48 hours, and one week post-procedure. Researchers will also monitor the frequency of pain medication use during this period. The trial is designed as a single-blind, randomized controlled trial sponsored by Ain Shams University, with participants aged 18 to 50 years. Overall, the study aims to correlate postoperative pain with the amount of debris pushed out during root canal irrigation.

Correlation Between Postoperative Pain and Apical Extrusion of Different Irrigation Activation Techniques