Actively Recruiting

Age: 3Months +
All Genders
NCT05196789

Diagnosis and Phenotype Characterisation Using Genomics in Patients With Inherited Bone Marrow Failure (IBMDx Study)

Led by Peter MacCallum Cancer Centre, Australia · Updated on 2024-11-07

350

Participants Needed

1

Research Sites

193 weeks

Total Duration

On this page

Sponsors

P

Peter MacCallum Cancer Centre, Australia

Lead Sponsor

N

National Health and Medical Research Council, Australia

Collaborating Sponsor

AI-Summary

What this Trial Is About

This project seeks to perform whole genome sequence (WGS) and whole transcriptome sequence (WTS) analysis on 350 patients with suspected inherited bone marrow failure syndromes and related disorder (IBMFS-RD) in order to increase the genomic diagnostic rate in IBMFS.

CONDITIONS

Official Title

Diagnosis and Phenotype Characterisation Using Genomics in Patients With Inherited Bone Marrow Failure (IBMDx Study)

Who Can Participate

Age: 3Months +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 3 months or older
  • Able to provide informed consent or have a parent/guardian provide consent
  • Clinical or pathological diagnosis or suspected diagnosis of inherited bone marrow failure syndrome or related disorder (IBMFS-RD) as determined by the study team
Not Eligible

You will not qualify if you...

  • Diagnosed with an acquired bone marrow failure syndrome, including acquired aplastic anemia or hypoplastic myelodysplastic syndrome
  • Already have a confirmed genetic diagnosis for the patient's blood condition

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Peter MacCallum Cancer Centre

Melbourne, Victoria, Australia

Actively Recruiting

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Research Team

K

Kelsey Man, PhD

CONTACT

P

Piers Blombery, MBBS(Hons)

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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