Actively Recruiting
Distribution Characteristics of Helicobacter Pylori
Led by Jilin University · Updated on 2025-11-28
231
Participants Needed
1
Research Sites
10 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study aimed to analyze the distribution characteristics of Helicobacter pylori（H. pylori） in varying stages of atrophic gastritis and early gastric cancer using immunohistochemical staining, with the goal of providing guidance for the early screening of gastric cancer. A retrospective analysis was conducted on gastric biopsy cases that underwent H. pylori immunohistochemical staining at our center from March 1, 2023, to August 15, 2025. Cases were classified into non-atrophic and atrophic groups based on the presence or absence of gastric atrophy. All cases were further divided into non-open and open atrophy groups and additionally into early gastric cancer and non-cancer groups. The distribution of H. pylori across subgroups was compared, and multivariate analyses were performed to identify risk factors associated with the development of early gastric cancer.
CONDITIONS
Official Title
Distribution Characteristics of Helicobacter Pylori
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 80 years
- Positive Helicobacter pylori immunohistochemical test performed at the study center
You will not qualify if you...
- Biopsies not collected from both the greater and lesser curvatures of the gastric antrum and body
- History of stomach surgery
- Suspected autoimmune gastritis observed by endoscopy
- Liver cirrhosis
- Severe illnesses such as advanced cancer or kidney failure
- Diagnosis of advanced gastric cancer or gastric lymphoma
AI-Screening
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Trial Site Locations
Total: 1 location
1
the First Hospital of Jilin University
Changchun, Jilin, China, 130021
Actively Recruiting
Research Team
D
Dong Yang, Doctor
CONTACT
H
Hong Xu, Professor
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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