Actively Recruiting
Early Rehabilitation Using Head Impulse Test for Acute Vestibular Deficit
Led by Hospices Civils de Lyon · Updated on 2025-05-16
26
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
The vestibulo-ocular reflex (VOR) helps maintain stable vision during head movements by causing the eyes to move in compensation. This reflex originates from the peripheral vestibular system and is especially important for rapid head movements, as assessed by the Head Impulse Test (HIT). In cases of acute unilateral vestibular deficit (AUVD), a compensatory eye movement called a catch-up saccade helps refocus vision. This study evaluates how early physiotherapy using the HIT might promote the learning and development of these catch-up saccades to improve recovery after vestibular damage, specifically after surgery to remove vestibular schwannomas, which cause a sudden and known vestibular deficit. Participants are randomly assigned to one of two groups: an experimental group that performs gaze stabilization exercises with head movements under video HIT control, and a control group that performs eye movement exercises without head movements (sham treatment). These exercises occur daily from the first to the sixth day after surgery. The experimental treatment involves fast, small head movements to stimulate the VOR, while the sham treatment involves visually guided eye movements without moving the head. Both treatments are supervised and use a device to monitor eye and head movements. During the study, participants will undergo various assessments including measurement of the first substitution saccade latency at several time points after surgery, balance and gait evaluations, and quality of life questionnaires before surgery and during follow-up visits at 7 days, 45 days, and three months post-surgery. The study also tracks saccade amplitude and latency daily during the first week after surgery. These evaluations help researchers understand how early rehabilitation affects recovery and visual function after acute vestibular deficit caused by surgery.
CONDITIONS
Brief Title
Early Rehabilitation Using Head Impulse Test for Acute Vestibular Deficit
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with unilateral vestibular schwannoma and planned surgery
- Vestibulo-ocular reflex gain greater than 0.50 on the affected side
- Vestibulo-ocular reflex gain greater than 0.80 on the healthy side
- All study information provided at least 15 days before surgery
- Consent obtained the day before surgery
You will not qualify if you...
- Prior radiotherapy treatment before surgery
- Repeat surgery
- Bilateral vestibular schwannomas
- Normal or corrected distance visual acuity less than 5/10
- Other causes explaining ataxic syndrome or oscillopsias
- Oculomotor paralysis or ocular instability in primary position
- Use of medications that affect eye movements, such as psychotropic drugs
- Cervical spinal instability contraindicating vHIT
- Cochlear implantation
- Unstable medical conditions
- Pregnant women
- Patients under guardianship
- Patients not affiliated with a social security scheme
- Participation in another interventional study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 6 days (post-operative days 1 to 6)
Participants receive either experimental treatment involving head movements or sham treatment involving only eye movements. Treatments occur under vHIT device control between post-operative days 1 to 6.
Daily visits for 6 days
Duration - Approximately 3 months
Participants are assessed for saccade latency, saccade amplitude, balance, gait, and quality of life at post-surgery Day 7, Day 45, and 3 months.
3 visits (Day 7, Day 45, and 3 months post-surgery)
Trial Site Locations
Total: 1 location
1
Pierre Wertheimer Hospital - Neurological Hospital
Bron, France, 69677
Actively Recruiting
Research Team
L
LAGADEC VL VINCENT
H
HERMANN RH Ruben, MD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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