Actively Recruiting
Effects of Tranexamic Acid Irrigation on Impacted Third Molar Surgery
Led by Bezmialem Vakif University · Updated on 2025-06-24
20
Participants Needed
1
Research Sites
61 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Tranexamic acid (TXA) is an effective hemostatic agent used to reduce blood loss and the need for transfusion. It is a relatively safe drug with minimal significant side effects. The most commonly reported complications include nausea, diarrhea, and occasional orthostatic reactions. The increased risk of thromboembolic events associated with the drug is the most serious complication; however, this has not been reported in most clinical studies and remains uncertain. Based on experience from other types of surgeries, tranexamic acid appears to be safe for use without an increased risk of venous thrombosis. To mitigate systemic absorption and minimize undesirable side effects, TXA can be applied topically rather than intravenously, reducing the risk of venous thromboembolism.
CONDITIONS
Official Title
Effects of Tranexamic Acid Irrigation on Impacted Third Molar Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Indicated for the extraction of bilaterally impacted third molars with bone retention
- Systemically healthy patients aged 14 to 40 years
- No bleeding disorders
You will not qualify if you...
- Presence of systemic diseases affecting general health
- Diagnosed bleeding disorders
- Advanced infection or cysts related to the impacted tooth
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Bezmialem Vakıf Universty
Istanbul, Fatih, Turkey (Türkiye), 34093
Actively Recruiting
Research Team
T
Taha Pergel, Asist.Prof
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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