Actively Recruiting

Phase Not Applicable
Age: 8Years - 16Years
All Genders
Healthy Volunteers
ID07529119

Effect of Consuming a Mango and Chia-based Beverage on Modulating the Intestinal Microbiota in Obese Children

Led by Universidad Nacional de Caaguazu · Updated on 2026-04-14

100

Participants Needed

1

Research Sites

8 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating the effect of a mango and chia-based beverage on the gut microbiota of 100 Paraguayan children aged 8 to 16 years who have obesity. The study aims to characterize the gut bacteria in these children for the first time and assess whether this functional beverage can positively influence intestinal bacteria. Childhood obesity affects one in three school-age children in Paraguay, making this research important for potential new strategies. Participants will be randomly assigned to consume either a mango juice beverage or a mango and chia juice beverage for 6 weeks. Both beverages are given as 200 ml daily servings, 5 days a week. The study uses a double-blind design to compare these two drinks and their effects on gut microbiota. During the study, fecal samples will be collected before and after the 6-week intervention to analyze changes in the microbiota using 16S rRNA sequencing. Researchers will also measure body size and composition at the beginning and after 4 weeks of treatment. The study is sponsored by Universidad Nacional de Caaguazu and includes safety monitoring and follow-up until July 2026.

CONDITIONS

Brief Title

Effect of Consuming a Mango and Chia-based Beverage on Modulating the Intestinal Microbiota in Obese Children

Who Can Participate

Age: 8Years - 16Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Children aged 8 to 16 years from Paraguay
  • Stratified by BMI including those with and without excess weight
Not Eligible

You will not qualify if you...

  • Allergy to mango or chia

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - 6 weeks

Participants consume either a mango juice or a mango and chia juice beverage daily for 6 weeks, 200 ml per day, 5 days a week.

Weekly visits for up to 6 weeks

Trial Site Locations

Total: 1 location

1

UNCA

Coronel Oviedo, Paraguay

Actively Recruiting

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Research Team

J

Julieta Mendez, Msc

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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