Studying How Enamel Matrix Derivatives Affect Gum Thickness Around Dental Implants in Adults

What this Trial Is About

Researchers are evaluating the effect of Enamel Matrix Derivatives EMD on the thickness of gum tissue around dental implants. The study tests whether applying EMD under the gum flap during implant uncovering increases mucosal tissue thickness and keratinized tissue width compared to not using EMD. This is a randomized controlled trial sponsored by The University of Texas Health Science Center at San Antonio. Participants will be divided into two groups one receiving EMD applied under the gum flap during the second stage implant uncovering, and the other receiving no EMD. The EMD application adds about 5 to 10 minutes to the procedure. All patients will have follow-up visits at 14 days for suture removal, and at one and three months for intraoral scans to assess soft tissue changes. The study treatment is performed during routine implant care. Participants will undergo intraoral scans at one and three months after treatment to measure mucosal thickness and changes in keratinized mucosal width. Follow-up visits coincide with standard care appointments, minimizing extra visits. Study participation concludes at the three-month visit, during which researchers collect important data to evaluate the impact of EMD on gum tissue around implants.

The Effect Of Enamel Matrix Derivatives On Gingival Tissue Thickness