Actively Recruiting
Effect of Raised Head of the Bed on Lying Blood Pressure in Autonomic Failure
Led by Vanderbilt University Medical Center · Updated on 2025-11-06
44
Participants Needed
1
Research Sites
331 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Many persons with autonomic failure often have high blood pressure when lying down (supine hypertension). This study is exploring the impact of decreased venous return to the heart (achieved by raising the head of the bed) to lessen supine blood pressure. If decreased venous return to the heart is effective at lowering supine blood pressure, these approaches may be utilized to treat supine hypertension non-pharmacologically. Raising the head of the bed decreases the amount of blood returning to the heart due to the effects of gravity. In this case, the decreased blood return to the heart may decrease blood pressure.
CONDITIONS
Official Title
Effect of Raised Head of the Bed on Lying Blood Pressure in Autonomic Failure
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with autonomic failure and supine hypertension from all races
- Males and females aged 18 to 85 years
You will not qualify if you...
- Medical students
- Pregnant women
- High-risk patients such as those with heart failure, symptomatic coronary artery disease, liver impairment, history of stroke or myocardial infarction
- History of serious allergies or asthma
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Vanderbilt University Medical Center
Nashville, Tennessee, United States, 37232
Actively Recruiting
Research Team
B
Bonnie K Black, RN
CONTACT
L
Luis E. Okamoto, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
TREATMENT
Number of Arms
4
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