Observing How Trendelenburg Position Affects Brain Activity and Oxygen Levels During Laparoscopic Hysterectomy in Adult Women

What this Trial Is About

This research aims to understand how the Trendelenburg position, often used during laparoscopic pelvic surgery, affects brain monitoring during general anesthesia in adult female patients undergoing elective laparoscopic hysterectomy. Specifically, it evaluates whether this position changes the Patient State Index PSI, which measures anesthetic depth from EEG signals, and whether these changes relate to cerebral oxygen levels and other vital signs. The study is observational and does not introduce any new treatments or interventions. Participants will receive standard anesthesia care and routine monitoring including heart rate, blood pressure, oxygen saturation, and end-tidal carbon dioxide. In addition to these, non-invasive sensors will record the PSI and frontal cerebral oxygen saturation rSO2 throughout the surgery. Measurements will be taken at key times such as before anesthesia, after intubation, after creating pneumoperitoneum, and during the Trendelenburg position. No extra procedures will be performed beyond routine clinical practice. During the surgery, researchers will collect data on PSI, cerebral oxygen saturation, mean arterial pressure, heart rate, and other physiological parameters at specific time points to observe any changes caused by patient positioning. This information will help clarify how body position influences brain monitoring and anesthetic depth readings. The study will run until December 2026, and participation involves only the observational recording of routine clinical and anesthesia monitoring data.

Effect of Trendelenburg Position on Patient State Index