Actively Recruiting
Differential Effects of High-Intensity Interval Training Versus Time-Restricted Eating on Type 2 Diabetes Risk in Youth and Younger Adults
Led by Syracuse University · Updated on 2025-10-10
40
Participants Needed
1
Research Sites
13 weeks
Total Duration
On this page
Sponsors
S
Syracuse University
Lead Sponsor
S
State University of New York - Upstate Medical University
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are studying the effects of two different lifestyle interventions on heart and metabolic health markers in overweight or obese adolescents and young adults aged 14 to 30 years. The study aims to compare high-intensity interval training (HIIT) and time-restricted eating (TRE) over a period of four weeks to see which approach better improves factors linked to type 2 diabetes risk and cardiovascular disease. Obesity is a major health concern linked to these conditions, making this research important for young people at increased risk. Participants are randomly assigned to one of three groups: a HIIT group, a TRE group, or a control group. The HIIT group performs supervised sessions on a stationary bike three times per week, involving short bursts of intense exercise followed by rest. The TRE group restricts their calorie intake to a 10-hour daily window, choosing a consistent timing for meals, with guidance on calorie needs. The control group continues their usual lifestyle without changes. Each intervention lasts four weeks. Throughout the study, participants will have various measurements taken at the start and end of the four weeks, including weight, height, body mass index, waist and hip size, blood pressure, blood sugar, insulin, cholesterol levels, and inflammatory markers. Heart rate and exertion levels are monitored during exercise sessions. The researchers will assess changes in these biomarkers to understand how each intervention affects cardiometabolic health. The total participation time is approximately one month for each individual.
CONDITIONS
Brief Title
Effects of HIIT vs. TRE on Type 2 Diabetes Risk
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adolescents aged 14 to 17 years with a BMI at or above the 85th percentile for their sex and race
- Young adults aged 18 to 30 years with a BMI of 25 kg/m2 or higher
You will not qualify if you...
- Having chronic medical conditions such as heart disease, arrhythmias, diabetes, thyroid disease, bleeding disorder, pulmonary disease, hypertension, hepatorenal disease, musculoskeletal disorder, neuromuscular or neurological disease, autoimmune disease, cancer, peptic ulcers, anemia, or chronic infection like HIV
- Current or recent use of medications affecting heart, lung, thyroid, cholesterol, blood sugar, blood pressure, hormones, mental health, or neuromuscular functions
- Having a pacemaker implanted
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 4 weeks
Participants receive either a 4-week high-intensity interval training program three times per week using a stationary bicycle, or follow a 4-week time-restricted eating plan consuming all calories within a chosen 10-hour window daily, or maintain their usual lifestyle without intervention.
Weekly visits for up to 4 weeks for assessments and supervision
Trial Site Locations
Total: 1 location
1
Syracuse University
Syracuse, New York, United States, 13244
Actively Recruiting
Research Team
W
Wonhee Cho, MS, PhD Candidate
J
Joon Young Kim, PhD, PhD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
3
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