Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
ID03155854

The Effects of Prophylactic Limited Palmar Fasciectomy on Surgical Outcomes and Scarring for Dupuytren's Contracture Patients With Pretendinous Cord - Prospective Randomized Clinical Study (Pilot)

Led by Mayo Clinic · Updated on 2026-03-16

50

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

This research focuses on patients diagnosed with trigger finger who also have a thickened Dupuytren's pretendinous cord and have chosen surgery over medical treatment. The study aims to evaluate a new surgical technique designed to reduce complications such as scarring, stiffness, pain, and loss of motion that can occur after trigger finger surgery when a Dupuytren's cord is present. Participants will be randomly assigned to one of two surgical approaches: either removal (excision) of the involved Dupuytren's fascia or division and incision of the pretendinous cord. This comparison will help determine if removing the cord reduces scarring and other complications compared to simply cutting it. Throughout the study, researchers will closely monitor participants' scar progression using validated scales, including the Vancouver Scar Scale and the Patient and Observer Scar Assessment Scale. These assessments will occur from baseline up to one year post-surgery. The study is sponsored by Mayo Clinic and involves no masking or blinding. Participants' experience and outcomes will be followed over this period to better understand the surgical effects on scarring and hand function.

CONDITIONS

Brief Title

The Effects of Prophylactic Limited Palmar Fasciectomy on Surgical Outcomes and Scarring

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults 18 years of age or older
  • Clinical diagnosis of trigger finger with co-existing pretendinous cord
  • Failed non-operative treatment or have chosen surgical treatment
Not Eligible

You will not qualify if you...

  • Under 18 years of age

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Surgery and Immediate Post-operative Care

Duration - 1 day

Participants undergo surgery to either excise or divide the pretendinous cord as part of a targeted palmar fasciectomy procedure.

1 surgical visit (in-person)

Post-operative Follow-up

Duration - Up to 1 year

Participants are monitored for surgical outcomes, scarring, and potential complications over the following year.

Multiple follow-up visits over 1 year

Trial Site Locations

Total: 1 location

1

Mayo Clinic

Rochester, Minnesota, United States, 55905

Actively Recruiting

Loading map...

Research Team

S

Sanjeev Kakar, MD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

Similar Trials

Effectiveness of Night Splinting After Percutaneous Needle F...

Dupuytren Contracture

Actively Recruiting

3 locations

Advancing Dupuytren's Contracture Treatment: a Clinical Pros...

Dupuytren Contracture

Actively Recruiting

1 location

Percutaneous Needle Fasciotomy With or Without Corticosteroi...

Dupuytren Contracture

Actively Recruiting

1 location

Frequently Asked Questions

Have more questions? Get in touch with our team for quick support

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here