Actively Recruiting

Phase 3
Age: 18Years +
All Genders
NCT06189859

Electrosurgical Modes for Endoscopic Submucosal Dissection in Peroral Endoscopic Esophageal Myotomy

Led by Cairo University · Updated on 2025-05-13

52

Participants Needed

1

Research Sites

71 weeks

Total Duration

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AI-Summary

What this Trial Is About

Peroral endoscopic esophagel myotomy (POEM) is a third space endoscopy technique that depends on creating a submucosal tunnel to expose the esophageal muscle and eventually perform an esophageal myotomy. Submucosal dissection can be performed using numerous electrosurgical modes. Spray coagulation has been anecdotally favored by many endoscopists due to its high coagulation power and assumed safety. Recently, Precisect mode has been developed, it has theoretical advantages of very minimal tissue penetration and minimal to no charring effect. In this trial, the investigators compare the efficacy and safety of both electrosurgical modes in POEM procedures.

CONDITIONS

Official Title

Electrosurgical Modes for Endoscopic Submucosal Dissection in Peroral Endoscopic Esophageal Myotomy

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients undergoing POEM procedure for any esophageal motility disorder
  • Esophageal motility disorder confirmed by high-resolution manometry and gastroscopy
Not Eligible

You will not qualify if you...

  • Esophageal varices
  • Esophageal neoplasms
  • Non-correctable coagulopathy
  • Failure to provide an informed consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Cairo University

Cairo, Egypt, 11562

Actively Recruiting

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Research Team

H

hany Shehab, MD, FRCP

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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