Actively Recruiting
Estimating Risk of Respiratory Infections Attributable to CFTR Heterozygosity
Led by Philip Polgreen · Updated on 2026-01-07
160
Participants Needed
1
Research Sites
236 weeks
Total Duration
On this page
Sponsors
P
Philip Polgreen
Lead Sponsor
N
National Institutes of Health (NIH)
Collaborating Sponsor
AI-Summary
What this Trial Is About
A research team member will brush the inferior surface of the subjects' middle turbinate (nasal cavity) using a cytology brush to obtain the cells needed to perform our functional respiratory assays. An individual trained in phlebotomy will draw one 3 ml lavender top tube of blood to test c-reactive protein, calprotectin, and lactoferrin. They will also draw a 5 ml gold top serum separator tube of blood to test fibroblast growth factor-19. The participant will answer questions from the baseline survey and report their current medications interview-style with the research team member.
CONDITIONS
Official Title
Estimating Risk of Respiratory Infections Attributable to CFTR Heterozygosity
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Previously tested and shown to be a CF carrier (for CF Carrier group)
- English-speaking (for CF Carrier group)
- Previously tested and shown not to be a CF carrier or CF patient (for Control group)
- English-speaking (for Control group)
You will not qualify if you...
- Currently sick with a respiratory infection
- Prisoner status
- Unable to provide own written, informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Iowa Hospitals and Clinics
Iowa City, Iowa, United States, 52242
Actively Recruiting
Research Team
P
Philip M Polgreen, MD
CONTACT
S
Shelby L Francis, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here