Actively Recruiting
European Association of Cardiovascular Imaging Multiple and Mixed Valvular Disease Study
Led by Assistance Publique - Hôpitaux de Paris · Updated on 2024-06-03
1500
Participants Needed
1
Research Sites
286 weeks
Total Duration
On this page
Sponsors
A
Assistance Publique - Hôpitaux de Paris
Lead Sponsor
E
European Association of Cardiovascular Imaging
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study aims to investigate the prevalence and characteristics of multiple and mixed valvular heart disease (MMVD), which includes combinations of stenotic or regurgitant lesions on cardiac valves. The research will be conducted as a multicenter observational study, involving several centers worldwide, and will have a one-year follow-up period (with a possible extension to 5 years). The primary aim is to determine the proportion of MMVD among patients evaluated for valvular heart disease. Secondary aims include the evaluation of the epidemiologic distribution of clinical, biological, and cardiovascular imaging characteristics at baseline, management strategies, and their impact on prognosis. The study will also evaluate clinical outcomes such as mortality, hospitalization for heart failure, and changes in echocardiographic parameters. This research aims to provide valuable insights into the diagnosis, management, and prognosis of MMVD, addressing an important knowledge gap in this area.
CONDITIONS
Official Title
European Association of Cardiovascular Imaging Multiple and Mixed Valvular Disease Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Patient referred to the cardiovascular imaging department
- Diagnosis of multiple and mixed valvular heart disease confirmed by transthoracic echocardiography
- Multiple valvular heart disease: at least 2 moderate to severe valve diseases involving 2 or more different valves according to ESC guidelines
- Mixed valvular heart disease: at least moderate stenosis and at least moderate regurgitation of a single valve according to ESC guidelines
- Patient consents to have their data included in the study
You will not qualify if you...
- History of prior valve surgery or percutaneous valve intervention on valves other than those involved in the current multiple or mixed valvular heart disease
- Acute infective endocarditis at time of evaluation or within the last 6 months
- Complex congenital heart diseases
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Assistance Publique Hôpitaux de Paris
Paris, Île-de-France Region, France, 75010
Actively Recruiting
Research Team
T
Théo PEZEL, MD PhD
CONTACT
A
Alexandre UNGER, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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