Actively Recruiting
AI Assisted Screening for VHD Using Routine Chest CT Scans
Led by Second Affiliated Hospital, School of Medicine, Zhejiang University · Updated on 2026-05-12
3000
Participants Needed
3
Research Sites
34 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This is a prospective, multicenter study designed to validate a deep learning model for screening valvular heart diseases using routine, non-contrast chest computed tomography (CT) scans. The primary objective is to evaluate the model's diagnostic performance, with the sensitivity serving as the primary efficacy endpoint. Secondary endpoints will include other performance metrics such as area under the receiver operating characteristic curve (AUC), specificity, and accuracy, etc.
CONDITIONS
Official Title
AI Assisted Screening for VHD Using Routine Chest CT Scans
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Complete electronic health record available
- Underwent non-contrast chest CT between November 1, 2025 and November 1, 2026 in any medical setting
- AI predicts moderate or severe valvular heart disease, or clinical intervention is required, or selected negative cases from sampling
You will not qualify if you...
- Poor-quality non-contrast chest CT images
- Incomplete clinical records with missing critical diagnostic, treatment, imaging, surgical, medical history, or lab test information
- Presence of prosthetic valve implants of any type
- Other abnormalities or conditions that investigators determine require exclusion
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
Renmin Hospital of Wuhan University
Wuhan, Hubei, China
Actively Recruiting
2
Xinjiang Uygur Autonomous Region People's Hospital
Ürümqi, Xinjiang, China
Actively Recruiting
3
The Second Affiliated Hospital of Zhejiang University School of Medicine
Hangzhou, Zhejiang, China
Actively Recruiting
Research Team
J
Jian'an Wang, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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