Studying Cognitive Changes After Bariatric Surgery in Adults with Morbid Obesity Using Virtual Reality and Neuropsychological Tests

What this Trial Is About

Obesity is a chronic, multifactorial disease linked to increased risks of cognitive decline and neurodegenerative disorders such as Alzheimers. This research aims to evaluate how bariatric surgery, which reduces fat and systemic inflammation, may impact cognitive function using virtual reality and neuropsychological testing. The study will compare cognitive performance before and after surgery to better understand factors predicting improvement. Participants with morbid obesity who are candidates for bariatric surgery will be included. Cognitive function will be assessed with the Neurotracker virtual reality tool three times weekly for two weeks before surgery, then again at 3 and 6 months post-surgery. The Neuropsi neuropsychological battery will be administered once before surgery and repeated at 6 months. The study includes a control group without obesity for comparison. During the study, participants will undergo multiple Neurotracker sessions totaling 80 trials per visit across 9 visits and Neuropsi assessments at baseline and 6 months. Researchers will analyze changes in cognitive performance after bariatric surgery. The study will monitor outcomes over 6 months and aims to provide insights into cognitive benefits from weight loss surgery and the predictors of these effects.

Evaluation of Cognitive Improvement After Bariatric Surgery Using a Virtual Reality Program and the Neuropsi Neuropsychological Battery