Healthy older observers show equivalent perceptual-cognitive training benefits to young adults for multiple object tracking.
Isabelle Legault, Rémy Allard, Jocelyn Faubert
https://pubmed.ncbi.nlm.nih.gov/23761025Actively Recruiting
Phase Not Applicable
Age: 18Years - 65Years
All Genders
Healthy Volunteers
ID07229924
Effect of Bariatric Surgery on Cognitive Performance Using Virtual Reality and the Neuropsi Neuropsychological Battery
Led by Hospital General de México Dr. Eduardo Liceaga · Updated on 2025-11-17
42
Participants Needed
2
Research Sites
35 weeks
Total Duration
On this page
Sponsors
H
Hospital General de México Dr. Eduardo Liceaga
Lead Sponsor
U
Université de Montréal
Collaborating Sponsor
AI-Summary
What this Trial Is About
Obesity is a chronic, multifactorial disease linked to increased risks of cognitive decline and neurodegenerative disorders such as Alzheimer's. This research aims to evaluate how bariatric surgery, which reduces fat and systemic inflammation, may impact cognitive function using virtual reality and neuropsychological testing. The study will compare cognitive performance before and after surgery to better understand factors predicting improvement. Participants with morbid obesity who are candidates for bariatric surgery will be included. Cognitive function will be assessed with the Neurotracker virtual reality tool three times weekly for two weeks before surgery, then again at 3 and 6 months post-surgery. The Neuropsi neuropsychological battery will be administered once before surgery and repeated at 6 months. The study includes a control group without obesity for comparison. During the study, participants will undergo multiple Neurotracker sessions totaling 80 trials per visit across 9 visits and Neuropsi assessments at baseline and 6 months. Researchers will analyze changes in cognitive performance after bariatric surgery. The study will monitor outcomes over 6 months and aims to provide insights into cognitive benefits from weight loss surgery and the predictors of these effects.
CONDITIONS
Brief Title
Evaluation of Cognitive Improvement After Bariatric Surgery Using a Virtual Reality Program and the Neuropsi Neuropsychological Battery
Who Can Participate
Age: 18Years - 65Years
All Genders
Healthy Volunteers
Eligibility Criteria
You may qualify if you...
- Age between 18 and 65 years
- Diagnosis of morbid obesity with body mass index (BMI) over 40 kg/m2
- Or obesity grade II (BMI over 35 kg/m2) with related conditions such as diabetes, hypertension, heart disease, high cholesterol, fatty liver, metabolic syndrome, sleep apnea, or Pickwick syndrome
- Meets criteria for bariatric surgery
You will not qualify if you...
- Age under 18 or over 65 years
- Visual impairment
- Personal history of cerebrovascular events (stroke)
- History of drug addiction
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
1
2
3
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Surgery
Duration - Day of surgery
Participants receive bariatric surgery to induce sustained weight loss by modifying gastrointestinal anatomy.
1 visit (in-person)
Treatment
Duration - Approximately 6 months
Participants complete NeuroTracker cognitive evaluation sessions before surgery, and at 3 months and 6 months after surgery to assess cognitive improvement.
9 visits total across pre-surgery and post-surgery assessments
Trial Site Locations
Total: 2 locations
1
Faubert Lab
Montreal, Quebec, Canada, H3T 1P1
Withdrawn
2
Hospital General de México "Dr. Eduardo Licega"
Mexico City, Mexico City, Mexico, 06720
Actively Recruiting
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Research Team
A
Argelia Pérez Pacheco, PhD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
SINGLE_GROUP
Primary Purpose
OTHER
Number of Arms
2
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Published Research Related To This Trial
Bariatric analysis and reporting outcome system (BAROS).
H E Oria, M K Moorehead
https://pubmed.ncbi.nlm.nih.gov/9819079The Impact of Various Methods of Obesity Treatment on the Quality of Life and Mental Health-A Narrative Review.
Marcin Hachuła, Michał Kosowski, Kaja Zielańska...
https://pubmed.ncbi.nlm.nih.gov/36767489NEUROPSI ATTENTION AND MEMORY: a neuropsychological test battery in Spanish with norms by age and educational level.
Feggy Ostrosky-Solis, Ma Esther Gomez-Perez, Esmeralda Matute...
https://pubmed.ncbi.nlm.nih.gov/17848126Obesity, adipose tissue, and bariatric surgery.
María E Frigolet, Kim Dong-Hoon, Samuel Canizales-Quinteros...
https://pubmed.ncbi.nlm.nih.gov/32115585[Not Available].
Ismael Campos-Nonato, Óscar Galván-Valencia, Lucía Hernández-Barrera...
https://pubmed.ncbi.nlm.nih.gov/38060949