Actively Recruiting
Evaluation of the Efficacy of E2R Hypnotherapy in the Management of Chronic Insomnia in Primary Care (HypERR)
Led by Rennes University Hospital · Updated on 2026-04-02
136
Participants Needed
35
Research Sites
78 weeks
Total Duration
On this page
Sponsors
R
Rennes University Hospital
Lead Sponsor
U
University of Rennes
Collaborating Sponsor
AI-Summary
What this Trial Is About
In France, the treatment of chronic insomnia relies mainly on hypnotic drugs in routine care, despite the high level of iatrogenicity. Cognitive-behavioral therapy (CBT) is recommended by the HAS as a non-pharmaceutical first-line therapy for chronic insomnia. Despite evidence of their efficacy in chronic insomnia, these therapies remain underdeveloped in France (few practitioners, time-consuming for the patient). Hypnotherapy is another non-drug intervention suitable for routine outpatient care. Among the hypnosis methods practiced in France, E2R (Emotion, Regression, Repair) is a hypnotherapy method used in general practice, particularly for chronic insomnia. To date, no clinical trials have been carried out to demonstrate its effectiveness in this pathology. The HypERR study is a multicenter, randomized, open-label study designed to evaluate the efficacy of a hypotherapy method called E2R in the management of chronic insomnia, by comparing it with standard care (without hypnosis).
CONDITIONS
Official Title
Evaluation of the Efficacy of E2R Hypnotherapy in the Management of Chronic Insomnia in Primary Care (HypERR)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patient aged 18 or over
- Diagnosed with chronic insomnia according to DSM-5 criteria
- Experiencing at least one sleep problem: difficulty falling asleep, trouble staying asleep, or waking too early
- Sleep problems occurring at least 3 nights per week for at least 3 months
- Sleep issues causing significant social, work, or behavioral impairment
- Insomnia not caused by substance effects, medical conditions, or mental disorders
- Willing to attend four 30-minute hypnotherapy sessions over 6 weeks
- Treating physician is the study investigator
- Able to give free, informed, written consent
- Affiliated with the French social security system
You will not qualify if you...
- Received any hypnotherapy sessions in the past 5 years
- Participating in another study for insomnia or sleep-related conditions
- Unable to complete self-administered questionnaires
- Poor or no understanding of French
- Unable to attend hypnotherapy sessions
- Deaf or hard-of-hearing without hearing aids
- Under legal protection or deprived of liberty
- Pregnant or breastfeeding women
AI-Screening
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Trial Site Locations
Total: 35 locations
1
Cabinet médical
Bain-de-Bretagne, France
Actively Recruiting
2
Cabinet médical de Plaisance
Bouaye, France
Actively Recruiting
3
Cabinet médical de Plaisance
Bouaye, France
Actively Recruiting
4
Cabinet médical de Breteil
Breteil, France
Actively Recruiting
5
Cabinet médical
Cesson-Sévigné, France
Actively Recruiting
6
Cabinet médical du Linon
Combourg, France
Actively Recruiting
7
Cabinet médical Sycamore
Contres, France
Withdrawn
8
Cabinet médical de Corps Nuds
Corps-Nuds, France
Not Yet Recruiting
9
Cabinet médical des Embruns
Crac'h, France
Actively Recruiting
10
Pôle Santé Physiomast
Dol-de-Bretagne, France
Actively Recruiting
11
MSP de l'Esplanade
Guer, France
Actively Recruiting
12
Maison médicale
Iffendic, France
Actively Recruiting
13
Cabinet Médical Chantepie
Joué Les Tours, France
Actively Recruiting
14
Cabinet Médical de Jugon-Les-Lacs -Saint-Igneuc
Jugon-les-Lacs, France
Actively Recruiting
15
Maison médicale des Longrais
La Chapelle-des-Fougeretz, France
Actively Recruiting
16
Cabinet médical
La Chapelle-Saint-Ursin, France
Actively Recruiting
17
Cabinet médical du Lion d'Or
Nantes, France
Actively Recruiting
18
Maison médicale Laennec
Pleudihen-sur-Rance, France
Actively Recruiting
19
Maison De Santé De Ronsouze
Ploërmel, France
Actively Recruiting
20
Cabinet médical Les Petits Ponts
Pont-Saint-Martin, France
Actively Recruiting
21
Cabinet médical Les Petits Ponts
Pont-Saint-Martin, France
Actively Recruiting
22
Maison de Santé de Questembert
Questembert, France
Actively Recruiting
23
Cabinet médical Olec
Rennes, France
Actively Recruiting
24
Cabinet médical
Rennes, France
Actively Recruiting
25
Maison médicale pluridisciplinaire
Rouziers-de-Touraine, France
Actively Recruiting
26
Maison médical de Maen roch
Saint-Brice-en-Coglès, France
Actively Recruiting
27
Maison médicale
Saint-Gilles-Croix-de-Vie, France
Actively Recruiting
28
Maison médicale
Saint-Gilles-Croix-de-Vie, France
Actively Recruiting
29
Maison de soin du Couesnon
Saint-Ouen-des-Alleux, France
Actively Recruiting
30
Cabinet médical
Saint-Romain-sur-Cher, France
Actively Recruiting
31
Maison de santé
Sancerre, France
Actively Recruiting
32
Cabinet médical de la Blanchisserie
Sully-sur-Loire, France
Actively Recruiting
33
Maison de santé
Talensac, France
Actively Recruiting
34
Cabinet des médecins généralistes de TIGY
Tigy, France
Actively Recruiting
35
Cabinet médical
Vildé-Guingalan, France
Actively Recruiting
Research Team
A
Aurélie VEISLINGER
CONTACT
I
Isabelle LEROYER
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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