Actively Recruiting

Phase Not Applicable
Age: 15Years +
All Genders
ID06596408

Evaluation of Retinal Vascular Density in High Myopia Without Pathological Myopic Maculopathy Using OCTA

Led by Sohag University · Updated on 2024-09-19

50

Participants Needed

1

Research Sites

4 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating the macular vascular density in people with high myopia who do not have pathological myopic maculopathy. This cross-sectional observational study involves about 50 patients attending the ophthalmology outpatient clinic at Sohag Teaching Hospital. The study aims to understand vascular changes in the retina using a specialized imaging technique called optical coherence tomography angiography (OCTA). Participants will undergo evaluation with OCTA to measure their macular vascular density and central macular thickness. The study includes myopic patients with a spherical refractive error of -6 or more, and excludes those with other ocular or systemic diseases affecting eye circulation, previous eye surgeries or injuries, or pathological myopic maculopathy conditions. OCTA will also help exclude patients with pathological changes. During the study, patients will be assessed using OCTA scans and OCT imaging to gather data on retinal vascular density and macular thickness. The main outcome measured is the vascular density in high myopes over six months. Participants will attend outpatient clinic visits for these evaluations, with no treatment administered as part of the study. The study is sponsored by Sohag University and is expected to end in October 2025.

CONDITIONS

Brief Title

Evaluation of Retinal Vascular Density in High Myopia Without Pathological Myopic Maculopathy Using OCTA .

Who Can Participate

Age: 15Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • All myopic patients with axial high myopia (-6 spherical refractive error or more) of different age groups
Not Eligible

You will not qualify if you...

  • History of any other ocular diseases or systemic diseases that may affect ocular circulation
  • Previous intraocular surgery or ocular injury
  • Presence of pathological myopic maculopathy such as epiretinal membrane, foveoschisis, macular holes, lamellar holes, Lacquers cracks, choroidal neovascularization, or retinal atrophy

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Diagnostic Evaluation

Duration - Single visit at enrollment

Participants undergo optical coherence tomography angiography (OCTA) to evaluate macular vascular density and to exclude patients with pathological myopic maculopathy.

1 visit (in-person)

Trial Site Locations

Total: 1 location

1

Sohag University

Sohag, Sohag Governorate, Egypt, 82524

Actively Recruiting

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Research Team

S

Sara Magdy Mohammed, Master degree

I

Islam Awny Ahmed, Ass. Prof

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

OTHER

Number of Arms

1

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